nrrheum.2014.167 pf1

Nov 19, 2014

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Figure 1 Infection with JC virus is at first asymptomatic and presumably occurs at an early age by oral route. Calabrese, L. H. et al. (2014) Sorting out the risks in progressive multifocal leukoencephalopathy Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2014.167.

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progressive multifocal leukoencephalopathy
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nrrheum.2014.167 pf1

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Figure 1 Infection with JC virus is at first asymptomatic and presumably occurs at an early age by oral route Calabrese, L. H. et al.(2014) Sorting out the risks in progressive multifocal leukoencephalopathy Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2014.167

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Figure 1 Mechanisms by which aldosterone and/or MR activation induce oxidative stress, inflammation, and fibrosis. Brown, N. J. (2013) Contribution of aldosterone to cardiovascular and renal inflammation and fibrosis Nat. Rev. Nephrol. doi:10.1038/nrneph.2013.110.

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Figure 5 HR‑pQCT images showing increment and decline of cortical and trabecular vBMD during growth and ageing. Geusens, P. et al. (2014) High-resolution in vivo imaging of bone and joints: a window to microarchitecture Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2014.23.

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Figure 4 Comparison of IwFS sequences and DESS sequences for the detection of a meniscal tear using MRI. Guermazi, A. et al. (2013) MRI-based semiquantitative scoring of joint pathology in osteoarthritis Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2012.223.

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Figure 1 Correlation between testosterone plasma levels and different clinical, instrumental and sexual parameters. Corona, C. & Maggi, M. (2009) The role of testosterone in erectile dysfunction Nat. Rev. Urol. doi:10.1038/nrurol.2009.235.

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Figure 1 Whole-body positron emission tomography scan showing a small glucose-avid lesion in the pelvis just superior to the bladder in the region of the left adnexa. Santillan A and Bristow RE (2006) Paraneoplastic cerebellar degeneration in a woman with ovarian cancer

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Figure 1 Renal survival of patients in our study with pauci-immune crescentic glomerulonephritis with and without ANCAs. Permission obtained from the American Society of Nephrology  Chen, M. et al. Antineutrophil cytoplasmic autoantibody negative pauci-immune crescentic glomerulonephritis.

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Figure 1 CT scan of tumor progression showing enlarged right laterocervical lymph nodes (white arrows) and laryngeal tumor (black arrows). Ares C and Allal AS (2005) Long-term complete remission of laryngeal Kaposi's sarcoma after palliative

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FIGURE 1 Localization of potential relevant molecular targets in irritable bowel syndrome with the specific classes of agents discussed in this Review. Cremonini F and Talley NJ (2005) Treatments targeting putative mechanisms in irritable bowel syndrome

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Figure 1 Minor salivary gland biopsy, stained with hematoxylin-eosin, from a patient with Sj ö gren's syndrome. Nordmark G et al. (2006) Mechanisms of Disease: primary Sj ö gren's syndrome and the type I interferon system Nat Clin Pract Rheumatol 2: 26 2 – 269 doi:10.1038/ ncprheum0173.

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Figure 1 Combination treatment schema for patients with rectal cancer enrolled in a clinical trial. Willett CG et al . (2007) Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer Nat Clin Pract Oncol 4 : 316 –321 doi:10.1038/ncponc0813.

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Figure 1 Results of cardiac function tests in the phase III trial of lapatinib plus capecitabine for metastatic breast cancer. Permission obtained from Geyer CE et al . (2006) Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med 355: 2733–2743.

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Table 3 Outcomes of therapeutic trials in mouse models of PTOA lacking data on genetic modification. Little, C. B. & Hunter, D. J. (2013) Post-traumatic osteoarthritis: from mouse models to clinical trials Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2013.72.

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Figure 1 Images of the case patient with an interstitial deletion of 5q22 encompassing the APC (adenomatous polyposis coli) gene, taken at 22 years of age. Heald B et al. (2007) Familial adenomatous polyposis in a patient with unexplained mental retardation

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Figure 2 Suggested algorithm for assessment, monitoring and management of patients with RA‑ILD on biologic therapy. Jani, M. et al. (2013) The safety of biologic therapies in RA‑associated interstitial lung disease Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2013.197.

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Figure 1 Upstream determinants (genes and molecular pathology) and downstream effects (clinical phenotypes) for the main neurodegenerative disorders. Pievani, M. et al. (2014) Brain connectivity in neurodegenerative diseases—from phenotype to proteinopathy

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