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ncponc0736-pf1

Figure 1 Schematic of oncolytic virotherapy mechanism of action: viral replication, cell killing, virus release and spread within cancer tissue but not normal tissues.

kerry-daniel
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ncponc0736-pf1

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  1. Figure 1 Schematic of oncolytic virotherapy mechanism of action: viral replication, cell killing, virus release and spread within cancer tissue but not normal tissues Reproduced from Kirn D et al. (2001) Replication-selective virotherapy for cancer: biological principles, risk management and future directions. Nat Med7: 781–787 Liu T-C et al. (2007) Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress Nat Clin Pract Oncol 4: 101–117 doi:10.1038/ncponc0736

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