Circulating L-DOPA as a Renal Dopamine Source

Jan 12, 2025

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This paper discusses the primary source of renal dopamine as circulating L-DOPA, freely filtered by the glomerulus. It explores the role of GRK4 in essential hypertension and salt sensitivity.

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renal dopamine
ldopa
essential hypertension
salt sensitivity

guy-emerson

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Circulating L-DOPA as a Renal Dopamine Source

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Figure 1 The principal source of renal dopamine is circulating L-DOPA, which is freely filtered by the glomerulus Felder RA and Jose PA (2006) Mechanisms of Disease: the role of GRK4 in the etiology of essential hypertension and salt sensitivity Nat Clin Pract Neprol2:637–650 doi:10.1038/ncpneph0301

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