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HUMAN BIOMONITORING Action 3 Consultative Forum on Environment Health 30th November 2006 in Luxembourg Update

ESBIO (FP6 SSP contract)Scientific Reports on: HBM inventory, ethics, data integration, guidelines for EU coordination, communication Implementation GroupThree Recommendations Feedback to

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HUMAN BIOMONITORING Action 3 Consultative Forum on Environment Health 30th November 2006 in Luxembourg Update

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    1. « HUMAN BIOMONITORING » Action 3 Consultative Forum on Environment & Health 30th November 2006 in Luxembourg Update on developments

    2. ESBIO (FP6 SSP contract) Scientific Reports on: HBM inventory, ethics, data integration, guidelines for EU coordination, communication Implementation Group Three Recommendations Feedback to & from national governments

    3. 1st IG Recommendation - 10/10/2005 2nd IG Recommendation - 3/3/2006 MS meeting: 5th April 2006 Consultative Forum: 19th April 2006 ESBIO/IG meeting in Berlin: 18-19 May 2006 Flash report to Consultative Forum 3rd IG Recommendation – 15/10/2006

    4. 3rd IG Recommendation Progress since 2nd IG Rec. Protocol for the EU Pilot Project: 2 (+1) scenarios Funding Highlights need for MS involvement Welcomes feedback from Cons. Forum

    5. Aim of the pilot project Feasibility study develop and test a coherent and harmonized EU HBM approach ; common protocols, guidelines, strategies, and scientific tools ensuring reliable and comparable data; a more effective use of resources; focus on the organisational, technical, logistical and infrastructural feasibility. Obtaining preliminary reference values of selected biomarkers from all participating Member States.

    6. SCENARIO 1: Basic for all participating Member States Population: women of childbearing age (22-50) and their children (6-11) Methylmercury in scalp hair Lead in whole blood Cadmium in urine Cotinine in urine

    7. SCENARIO 2: Additional & Facultative at least 5 Member States List contains examples, not exhaustive PHTHALATES: in urine [DEHP DINP and DBP metabolites] PAHs: in urine [Pyrene and Phenanthrene] BFRs: in blood [DBDE, TBBPA, Hexabromocyclododecane] PFCs: in blood [PFOA, PFOS, PFOSA] OP-Pesticides: in urine [Dimethylphosphate (DMP), Diethylphosphate, DEP), Di{m}ethylthiophosphate (D{M}ETP), p-Nitrophenol, etc.] Pyrethroids: in urine [4-Fluoro-3-phenoxybenzoic acid,cis/trans-3-(2,2- Dichlorovinyl)-2,2-dimethylcyclopropaneCA, cis-3-(2,2-Dibromovinyl)-2,2-DMCPCA 3-Phenoxybenzoic acid]

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