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SIFT. Milk Feed Guidance. A multi-centre randomised controlled trial of two speeds of daily increment of milk feeding in very preterm or very low birth weight infants. At Randomisation: Infant receiving < 30ml/kg/d of milk Feeds should be advanced at allocated rate
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SIFT • Milk Feed Guidance A multi-centre randomised controlled trial of two speeds of daily increment of milk feeding in very preterm or very low birth weight infants
At Randomisation: • Infant receiving < 30ml/kg/d of milk • Feeds should be advanced at allocated rate • as soon as possible after randomisation
Calculate milk volume on • Birth Weight or Current Weight (whichever is greater) • Prescribe total milk volume for that day using allocated increment • e.g. from 30 to 60ml/kg/d (fast) • from 30 to 48 ml/kg/d (slow) • Divide this total by the number of feeds you would normally give • 1 hourly = 24 feeds • 2 hourly = 12 feeds • 3 hourly = 8 feeds • For ease, rounding to nearest 0.5 ml is acceptable
Online calculator An online calculator is available via the randomisation program to assist with feed calculations.
For those who like charts FAST MILK FEED INCREASE(30 ml/kg/day increment on HOURLY feeds) In addition to the milk volume being given at the start of increasing the feeds • Larger 24 hour steps (bold) preferred • Smaller 8 hour steps also shown
SLOW MILK FEED INCREASE(18 ml/kg/day increment on HOURLY feeds) In addition to the milk volume being given at the start of increasing the feeds • Larger 24 hour steps (bold) preferred • Smaller 8 hour steps also shown
FAST MILK FEED INCREASE(30 ml/kg/day increment on 2 HOURLY feeds) In addition to the milk volume being given at the start of increasing the feeds • Larger 24 hour steps (bold) preferred • Smaller 8 hour steps also shown
SLOW MILK FEED INCREASE(18 ml/kg/day increment on 2 HOURLY feeds) In addition to the milk volume being given at the start of increasing the feeds • Larger 24 hour steps (bold) preferred • Smaller 8 hour steps also shown
What do I do if… • Feeds are stopped? • Start at previous rate and follow prescribed increment • Start from beginning and follow prescribed increment • Start from beginning and follow unit’s policy • All treatment and management are at clinician discretion • Record all data regardless of regimen adopted
What do I do if… • Baby has large gastric residuals? • Clinician discretion – but aim to prevent feeds being stopped or reduced without justification • Record all data
What do I do if… • Baby misses a days increment? • Increase at prescribed rate • Don’t try and make up time • Record all data If the data are recorded then what happened to the baby is captured
NPEU Clinical Trials Unit Department of Public Health University of Oxford Old Road Campus Oxford OX3 7LF T: 01865 617 919 F: 01865 289 740 E: sift@npeu.ox.ac.uk www.npeu.ox.ac.uk/sift Thanks for your attention Best of luck with the study!