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Active Transport Mechanisms

Active Transport Mechanisms. Primary active transport Secondary active transport Vesicular transport. Types of Pumps. Na+/K+ pump H+ pump H+/K+ pump Ca++ pump. Phosphorylation & dephosphorylation. Types of Pumps. Na+/K+ pump H+ pump H+/K+ pump Ca++ pump.

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Active Transport Mechanisms

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  1. Active Transport Mechanisms • Primary active transport • Secondary active transport • Vesicular transport

  2. Types of Pumps • Na+/K+ pump • H+ pump • H+/K+ pump • Ca++ pump

  3. Phosphorylation & dephosphorylation

  4. Types of Pumps • Na+/K+ pump • H+ pump • H+/K+ pump • Ca++ pump

  5. The importance of pumps for cell functions

  6. Secondary Active Transport

  7. Secondary Active Transport • Co-transport • Counter transport

  8. Vesicular Transport

  9. Formation of vesicles at ER

  10. Endocytosis

  11. Phagocytosis

  12. Receptor mediated endcytosis

  13. Exocytosis

  14. Control of Exocytosis

  15. Transcytosis

  16. Summary of Lectures -Homeostasis -Control of body functions by feed-back mechanisms to keep homeostasis -Functions of Cell organells (ER, Golgi complex, Mitochondria, Lisosomes) -Cytoskeletal structures and Functions:

  17. Plasma membrane - Membrane structure and function of lipids of plasma membrane including phospholipids, cholesterol and PIP2) -Functions of Protein structures (including channels, Carriers, receptors, Pumps, enzymes, cell markers, G proteins, adhesion molecules) -Activation of chemical gated channels

  18. Transport through plasma membranes Passive transport modalities -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion. -Facilitated diffusion: by carriers Differences in diffusion Kinetics between the previous modalities Equivalent Concentration of particles.

  19. Transport through plasma membranes Passive transport modalities -Osmosis: concept of osmotic pressure (Van’t Hoff’s law), Oncotic (Colloid-osmotic) pressure.Osmolarity, osmolality Hydrostatic pressure

  20. Transport through plasma membranes Active transport modalities - Primary active transport (ATP-ase carriers or Pumps) (functions of pumps: Na+/K+ pump, Ca++ pump, H+ pump, H+/K+ pump). - Secondary active transport (Na+ dependent carriers) examples

  21. Transport through plasma membranes Active transport modalities - Vesicular transport: endocytosis, phagocytosis, transcytosis, pinocytosis and exocytosis and its control in secretory cells.-

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