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High-Intensity Focused Ultrasound Therapy Array

High-Intensity Focused Ultrasound Therapy Array. May1005 Alex Apel Stephen Rashid Justin Robinson. Problem / Need Statement. Problem Traditional Tumor Removal: Invasive HIFU: Non-Invasive Tumor Removal Need Research tool to Control HIFU Therapy Array Independent Control of Transducers.

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High-Intensity Focused Ultrasound Therapy Array

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  1. High-Intensity Focused Ultrasound Therapy Array May1005 Alex Apel Stephen Rashid Justin Robinson

  2. Problem / Need Statement • Problem • Traditional Tumor Removal: Invasive • HIFU: Non-Invasive Tumor Removal • Need • Research tool to Control HIFU Therapy Array • Independent Control of Transducers

  3. Requirements & Wishes • Requirements • Generate Independent Waveform • 1.1 MHz • 500W Instantaneous Power • 0.01% - 1% Duty Cycle • Wishes • Collect Feedback Data • 50 M Samples / Sec • Provide Feedback Access • User Interface • Clean Interface to System • Specify waveform properties • Pulse Duty Cycle • Pulse Period • Pulse Count • Relative Phase

  4. System Architecture

  5. Risks • Loss of Team Member • Damage to Equipment • Lack of Expertise • Time Constraints • Budget Constraints

  6. Software Architecture RS-232 Micro GUI • Input • Generate Waveform • Process Feedback • Input • Relative Transducer Phase • Transducer Amplitude • Signal Period • Signal Duty Cycle • Start/Stop Generation • Output • Phase Control Logic Transducer Feedback Analog Hardware Transducer Transducer Transducer

  7. Software Prototype Architecture Micro • PWM • Two Channel Control • Hard Coded Waveform Control Logic Analog Hardware Transducer Transducer Transducer

  8. Software Implementation • User Interface • Serial Communication with MCU • Graphical Input • Microcontroller • Prototype Implementation • PWM: Direct Control • Final Implementation • PreliminarySerial Communication

  9. Software Testing & Evaluation • PC Software • Unit Testing of Serial Communication • Further Testing: On Hold • Microcontroller Software • Prototype Software

  10. Next Steps • Two-way Communication: MCU PC Software • Fabrication of PCB • Writing Waveforms to RAM • Reading Feedback from RAM

  11. Digital Architecture MCU Feedback RAM Waveform RAM Feedback RAM Waveform RAM ADC Analog Circuitry ADC Analog Circuitry

  12. Digital Implementation • Microcontroller • Acquisition Complete • Writing software • Paused for PCB Layout • Logic Circuitry • IC Acquisition Complete • Logical Layout Complete • PCB Layout Complete • PCB Routing in Progress • Prototype Software • Fully Implemented • Capable of bypassing Logic Circuitry • Critical for system prototype

  13. Digital Testing & Evaluation • Testing • Microcontroller • Test Code • Controls Waveform Directly • Logic Circuitry • Not Implemented • Prototype Software • Range of desired Waveforms • Evaluation • Microcontroller • System in place • Executes • Logic Circuitry • System ready for assembly • System easily modified • Bypassed • Prototype Software • Asserts Logic Circuitry Waveform

  14. Next Steps • Microcontroller • Complete Software • Use ribbon cable to physically connect to PCB • Logic Circuitry • Assemble the ordered PCB • Write and execute waveforms • Read back feedback data • Remove role of prototype code

  15. Analog Implementation • H-Bridge • Half-Bridge • HIP4081A controller

  16. Analog Architecture Half Bridge A Transducer From Micro Half-Bridge Controller High Voltage DC Power Supply Transducer Half Bridge B

  17. Analog Testing & Evaluation • Emulation testing • Problems • Potential • Low power transducer • High power transducer

  18. Next Steps • Further evaluation of half-bridge amplifier • Integration with logic circuitry • Expansion to more channels • Test with Transducer

  19. Lessons Learned • Prioritize System Features from Beginning • Controlling System Scope is Important • Order Extra Parts • Hardware Takes a Long Time to Realize • Knowing Your Tools is Key to Development Time • Benefit from Others Experience

  20. Acknowledgments Dr. Timothy Bigelow Dr. Randy Geiger Texas Instruments

  21. Questions?

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