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Schizophrenia is a mental disorder characterized by disorganized thinking, hallucinations, and inappropriate emotions. Delusions and hallucinations are key symptoms, with positive and negative manifestations. Biological factors such as dopamine receptors and genetic predisposition play a role. Treatment involves medication, skills training, and family support to manage symptoms and prevent relapse.
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Schizophrenia Psychosis involves loss of contact with reality, symptoms include: 1) Disorganized and deluded thinking 2) Disturbed perceptions (hallucinations) 3) Inappropriate emotions and actions
Schizophrenia Delusions: false beliefs not based on reality Hallucinations: perceptions in the absence of sensory stimulation, often hearing non existent voices
Schizophrenia • Positive symptoms: talk is disorganized and deluded, emotional expression (e.g., laughter, tears, or rage) is often inappropriate • Negative symptoms: toneless voices, expressionless faces (flat affect), or mute and rigid bodies
Schizophrenia • Chronic (process) develops gradually • Acute (reactive) develops rapidly in response to particular life stresses
Schizophrenia Biological observations include: • Increased receptors for dopamine • Frontal lobe underactivity • Enlarged ventricles (less cerebral tissue) Biological causes implicate: • Genetic predisposition • Mid-pregnancy viral infection of the fetus
Genetic Risk • General: 1% • Siblings: 8% • Fraternal Twins 18% • Identical Twins 48% • Parent 13% • Both parents 45%
Schizophrenia • Relapse frequency is related to stress and to double-bind situations. • Treatment: • Drugs that decrease dopamine (chlorpromazine, clozapine) • Skills training, family support • Tardive dyskenisia can be a side effect of chlorpromazine