Supplemental appendix 4

Supplemental appendix 4 EXAMPLES OF BLEEDING MANIFESTATIONS* Skin domain: slides 2 to 23Mucosal domain: slides 24 to 30 Organ domain: slides31 to 32 *Where not otherwise specified, pictures are taken from patients with primary ITP

Actual scale: 1 cm 2 cm 3 cm A crop of scattered petechiae Courtesy by M. Michel

Purpuric manifestations in a patient with septicemia and thrombocytopenia Courtesy by F. Rodeghiero

Allergic (maculopapular) skin reaction secondary to cephalosporin (should not be recorded) Courtesy by F. Rodeghiero

Recent scattered petechiae with confluence to form a purpuric macule (arrow) Courtesy by M. Michel

Synchronous recent scattered petechiae. Abrupt presentation in ITP Courtesy by F. Rodeghiero

Same patient. Synchronous recent scattered petechiae extending to the sole. Courtesy by F. Rodeghiero

Petechiae of various size and age Courtesy by F. Rodeghiero

Palpable purpura in a non thrombocytopenic patient Courtesy by F. Rodeghiero

Petechiae and one ecchymosis larger than a patient’s palm size Courtesy by R. Stasi

Six reddish-purple ecchymoses smaller than a patient’s palm size Courtesy by M. Michel

Leg ecchymoses and scattered petechiae (not recent) Courtesy by M. Michel

Several ecchymoses, one larger than patient’s palm size and no petechiae Courtesy by M. Michel

Old ecchymosis, dating more than 10-15 days and a small, recent one Courtesy by F. Rodeghiero

Extensive ecchymosis with underlying subcutaneous hematoma Courtesy by F. Rodeghiero

Simmetrical ecchymoses with underlying subcutaneous hematomas caused by self-administered LMWH in a patient with ITP and moderate thrombocytopenia (should not be recorded) Courtesy by F. Rodeghiero

Three old synchronous large ecchymoses and a few more recent petechiae Courtesy by F. Rodeghiero

Ecchymoses of various age Courtesy by F. Rodeghiero

Bullae and discoloration of skin not due to ITP (should not be recorded) Courtesy by F. Rodeghiero

Vaste ecchymosis secondary to constriction Courtesy by F. Rodeghiero

Old small ecchymoses (sometimes seen in healthy people, purpura simplex) Courtesy by F. Rodeghiero

An old ecchymosis Courtesy by F. Rodeghiero

Very old ecchymosis (weeks) and some more recent petechiae Courtesy by F. Rodeghiero

Hemorrhagic bullae of various age, two 1-day old on the left tongue margin Courtesy by M. Michel

Old (2-3 days) hemorrhagic bullae and facial petechiae of various age Courtesy by M. Michel

Recent hemorrhagic bullae (less than 2 days) Courtesy by F. Rodeghiero

Sublingual recente ecchymosis Courtesy by F. Rodeghiero

Partial hemorrhage in one eye and small peripalpebral ecchymosis in a patient with post-chemotherapy trombocytopenia Courtesy by F. Rodeghiero

Bilateral peripalpebral ecchymoses and complete subconjunctival hemorrhage in a patient with post-chemotherapy trombocytopenia Courtesy by F. Rodeghiero

Intracerebral hemorrage Courtesy by M. Michel

Pictorial Blood Assessment Chart In Rodeghiero et al, Haemophilia 2008; 14:68-75

Supplemental appendix 4

Supplemental appendix 4

Presentation Transcript

VIII. Appendix and supplemental information

Appendix : CV 4. Johannes Aslan

Appendix 4

Project 4 Supplemental Lecture

Appendix 4.A

Supplemental figure 4

Supplemental Figure 4

Supplemental Fig. 4

Chapter 4 Appendix

Appendix to Chapter 4

Supplemental Figure 4

Supplemental Fig.4

Supplemental Figure 4

Supplemental Appendix

Appendix B.4

Supplemental figure 4

Supplemental Figure S 4

Supplemental Figure 4

Appendix 4 (p. 1/7)

SUPPLEMENTAL FIGURE 4

APPENDIX 4

Supplemental Digital Content 4