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This study examines the effects of hypoxia and SB202190 treatment on hepatocellular cell viability. Results show enhanced cell survival under low oxygen conditions and SB202190 treatment. The findings suggest potential therapeutic strategies for liver diseases.
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A Panc5.04 A10.7 A38.44 *** ** *** *** *** ** ** ** B C Panc5.04 A38.44 ADM NDRG-1 *** ** ** Vehicle (10%FBS) Vehicle (1%FBS) SB202190 (10%FBS) SB202190 (1%FBS) Vehicle (10%FBS) Vehicle (1%FBS) SB202190 (10%FBS) SB202190 (1%FBS) Vehicle (10%FBS) Vehicle (1%FBS) SB202190 (10%FBS) SB202190 (1%FBS) Vehicle 20% O2 Vehicle 1%O2 SB202190 20% O2 SB202190 1%O2 Vehicle 20% O2 Vehicle 1%O2 SB202190 20% O2 SB202190 1%O2 *** * Fold Change Relative to Normoxia ** ** ** *** *** ** * *** * Panc5.04 A38.44 Supplemental Figure 4