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Explore the application of the scientific method through two intriguing cases - the mysterious beriberi disease and the discovery of penicillin. See how scientists identify problems, make observations, form hypotheses, conduct experiments, and draw conclusions. Learn about the importance of evidence-based reasoning in scientific breakthroughs.
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Scientific Method in Action Cases of Mystery
The Strange Case of BeriBeri • State the problem • A strange nerve disease attacks the people of the Dutch East Indies
The Strange Case of BeriBeri • What were the observations? • Weakness, loss of appetite, and death from heart failure
The Strange Case of BeriBeri • What was the hypothesis? • The disease is caused by bacteria.
The Strange Case of BeriBeri • How was the hypothesis tested? • They injected chickens with the bacteria from the blood of patients with beriberi.
The Strange Case of BeriBeri • Should the hypothesis be supported or rejected by the experiment? • Rejected, because all the chickens became ill, even those who were not injected.
The Strange Case of BeriBeri • What should the new hypothesis be? • If a person does not eat enough thiamin, then they will develop beriberi disease.
How Penicillin Was Discovered • Indentify the problem. • Mold was growing in the dishes with the bacteria.
How Penicillin Was Discovered • What were the observations? • A clear area existed around the mold because the bacteria had died.
How Penicillin Was Discovered • What was Fleming’s hypothesis? • The mold was producing a chemical that killed the bacteria.
How Penicillin Was Discovered • How was the hypothesis tested? • He grew mold in a broth and added it to the bacteria.
How Penicillin Was Discovered • Should the hypothesis be supported or rejected based on the experiment? • Supported, because the bacteria died.
How Penicillin Was Discovered • This experiment lead to the development of what major medical advancement? • Penicillin used as a medicine for bacteria.