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Reparative processes and cellular adaptations. SYLLABUS: RBP( Robbins Basic Pathology ) Chapter : Cell Injury , Adaptation , and Death Hypertrophy Hyperplasia Metaplasia Tissue Repair : Cell Regeneration and Fibrosis (al l). Reparative processes and cellular adaptations.
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Reparative processes and cellular adaptations • SYLLABUS: • RBP(Robbins Basic Pathology) Chapter: • CellInjury, Adaptation, and Death • Hypertrophy • Hyperplasia • Metaplasia • TissueRepair: CellRegeneration and Fibrosis(all)
Reparative processes and cellular adaptations 48-I Granulation tissue 48Foreign body granuloma 44Myocardial hypertrophy 192Benign prostatic hyperplasia (BPH) 287Columnar to squamous bronchial metaplasia
Granulation tissue • proliferating small blood vessels • proliferating fibroblasts • macrophages • - other inflammatory cells • other cellular elements of connective tissue • non numerous connective tissue fibers
Foreign body granuloma foreign-body type giant cells epithelioid cells other elements of granulation tissue
Foreign-body type giant cells (framed white) Langhans cells (framed blue)
Myocardial hypertrophy enlarged myocardial cells
Benign prostatic hyperplasia (BPH) nodularity due to:- glandular proliferation or dilation- fibrous and muscular proliferation of the stroma - foci of squamous metaplasia - small areas of infarction - papillary buds and infoldings of epithelium
Columnar to squamous bronchial metaplasia normal ciliated columnar epithelial cells of the bronchi replaced focally or widely by stratified squamous epithelium