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Type 1 Diabetes. Jennifer McVean, MD September 23, 2010. Outline. Type 1 diabetes: increasing incidence and prevalence Exciting research and developments in type 1 diabetes Juvenile Diabetes Research Foundation and The Walk to Cure Diabetes. Type 1 Diabetes. Autoimmune Disease
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Type 1 Diabetes Jennifer McVean, MD September 23, 2010
Outline • Type 1 diabetes: increasing incidence and prevalence • Exciting research and developments in type 1 diabetes • Juvenile Diabetes Research Foundation and The Walk to Cure Diabetes
Type 1 Diabetes • Autoimmune Disease • White blood cells attack & destroy islet cells in pancreas which produce insulin • Absolute insulin deficiency • Symptoms: polyuria, polydipsia, weight loss • Requires lifelong treatment with insulin given by injection or subcutaneous infusion
Type 1 Diabetes • One of the most common chronic diseases of childhood • In the US: • 13,000 new childhood diagnoses per year • Prevalence for ages 0-19 years is: 1/300 – 1/500 • Number of new patients annually has tripled in the past 20 years www.cdc.gov
T1D incidence is rising 3-5% per year Incidence /100,000/ yr in children aged 0-14 REWERS
Therapeutic Areas Immune Therapies Beta Cell Therapies Complications Therapies Glucose Control Stop the Attack! Restore Beta Cells! Prevent, Stop, Reduce! Tight Control!
What’s ahead… • http://abcnews.go.com/video/playerIndex?id=8046715
JDRF Mission: to find a cure for type 1 diabetes and its complications
Who is JDRF? • Founded in 1970 by parents of children with type 1 diabetes • Raises money and advocates for government spending for type 1 diabetes research • Global leader in funding research toward a cure for type 1 diabetes • Sets the agenda for diabetes research worldwide • Largest charitable funder of type 1 research
JDRF Has funded more than $1.4 billion in research JDRF annually receives top rankings from organizations that rate charities More than 80 percent of our expenditures directly support research and research-related education
Sunday, October 3 at Myrick Park 12pm Registration 1pm Walk