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EDUCATION. “Education is a progressive discovery of our own ignorance.” -Will Durant. CASE #3. HARD TICKS vs. SOFT TICKS. COMMONLY FOUND TICKS. Tick life cycle. Tick life cycle. Female lays 1,000 to 10,000 eggs before dying. Ticks. HOW TICKS INJURE ANIMALS:
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EDUCATION “Education is a progressive discovery of our own ignorance.” -Will Durant
Tick life cycle Female lays 1,000 to 10,000 eggs before dying
Ticks HOW TICKS INJURE ANIMALS: • Irritation of the bite wound • Vector for diseases • Neurotoxins in saliva of 12 different species • Clinical signs vary with disease Dx: finding tick; hxof exposure to wooded and grassy areas
Brown Dog Tick • The brown dog tick (Rhipicephalus sanguineus) • Transmits Ehrlichiosis in dogs • Brown dog ticks are found throughout the world. Dogs are the primary host for the brown dog tick for each of its life stages.
Ticks • Rx: Manually remove ticks • Grasp head parts close to skin with forceps (NOT HANDS) and pull backwards; no gasoline, cigarettes, etc. • Topical treatments (sprays, shampoos, powder, dips) • Collars • Topical systemic products • Client Info • Routinely check pets for ticks, esp after walks in parks, etc • Do not use bare hands to remove and kill ticks – blood may be infectious • Ticks will feed on humans
Tick paralysis Dermacentor variabilis Dermacentor andersoni Neurotoxin in saliva of gravid female
Burrowing Mites • Family Sarcoptidae – Small, round, live in skin tunnels. Short legs close to body. Cause mange. – Sarcoptes, Notoedres, Knemidocoptes Trixacarus • Family Demodicidae – Live in hair follicles. – Adults cigar shaped. – Demodex
Demodex • Inhabits hair follicles, sebaceous glands or apocrine sweat glands • D. canis • Normal inhabitant in small numbers • Spends entire life cycle on host • Immune system controls infestation • Genetic predisposition • Localized or generalized • Transmission • Have not seen dog-to-dog or dog-to-human transmission
Demodex • Demodex cati (right) • Demodex canis (left)
Demodex • D. cati • Similar to D. canis – lives in hair follicles • D. gati - 2nd most common demodex mite on cat • Fat (broad, blunted abdomen) • Lives more superficial in stratum corneum • More pruritic • Associated with immune suppression • Similar lesions to dogs
Demodex • Clinical Signs • Localized • Young dog (3m-1 y); • Alopecia esp on face • Erythema; crusty lesions • Not pruritic unless secondary infections are present • Generalized • Often febrile • Entire body surface involved • Can result in protein loss through wounds • Secondary bacterial infection - pustules • Dx – skin scraping - deep
Demodex • Tx • Localized – Rotenone (Goodwinol) topical daily or mupiricin (Bactroban) • Generalized • Mitaban (amitraz) dips q 7 days x 3-6 treatments or 2 negative skin scrapings • Side Effects – sedation for 12-24 hrs (up to 72 hrs) • Ivermectin: SQ repeat q 14 days OR PO SID x 60-90 days extralabel use – client sign a release form – Not herding breeds • Interceptor: 1/mo x 3 mo or more • Oral antibiotics for secondary bacterial infections • Client Info • Many animals outgrow demodex as they age • Not contagious to humans • Tx does not completely remove mites • If breeding dog, then do not treat and do not breed if does not clear on its own • Strongly recommend OHE with treatment or will relapse with heat cycles • Generalized form can be fatal.
Demodex Rx Approved Not FDA approved Approved SQ or PO
Demodex • Newer drugs and protocols • Ivermectin – lower initial dose due to side effects, then gradually increase dose over several days • SE: ataxia, bradycardia, mydriasis, resp arrest, salivation, stupor and tremors • Milbemycin (Interceptor) –PO SID x 30-45 days • Fewer Side effects • Expensive for large dogs • Continue for 4 weeks post 2nd negative skin scraping – may be cost prohibitive • moxidectin + Imidacloprid (Advantage Multi) • Only APPROVED treatments • Amitraz (Mitaban) • Moxidectin + imidacloprid in topical formulation (Advantage Multi) • Milbemycinoxime (Interceptor) orally
Burrowing Mites • Sarcoptes scabei
Sarcoptic Mange • Species specific • Adults live 4-5 weeks • Egg-larva-nymph-adult cycle • 17-21 days • Entire life cycle on skin • Infective in house environment for 24-36 hrs • Burrows under skin – stratum corneum • Hypersensitivity reaction
Sarcoptic mange • Clincal Signs • Red crusty lesions on ears, elbows and trunk • Intensely pruritic • Progressively more severe • DX – skin scraping; difficult to find mite • Tx – easily killed • Amitraz dip q 14 days • Ivermectin SQ or PO q 14 days (extralabel use) • Selamectin (revolution) – topically q 2 weeks x 3 treatments • Client Info – highly contagious to other dogs and humans