1 / 11

Clostridium botulinum

Clostridium botulinum. By: Ellie McCarthy AP Biology – Period 1&2. Scientific Classification. Domain : Bacteria Kingdom : Bacteria Division : Firmicutes Class : Clostridia Order : Clostridiales Family : Clostridiaceae Genus : Clostridium Species : C. botulinum

cisco
Download Presentation

Clostridium botulinum

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Clostridium botulinum By: Ellie McCarthy AP Biology – Period 1&2

  2. Scientific Classification • Domain: Bacteria • Kingdom: Bacteria • Division: Firmicutes • Class: Clostridia • Order: Clostridiales • Family: Clostridiaceae • Genus: Clostridium • Species: C. botulinum • Binomial name: Clostridium botulinum

  3. Characteristics • Gram positive • Shape: rod (bacilli) • Obligate anaerobe (chemautotroph) • Found in soil • Form in colonies • Motile

  4. Unique Structural Features • Produces oval, subterminalendospores • Can survive in most environments and are very hard to kill • Produces botulinum neurotoxins types A-G • Called botulin • Extremely toxic • Types A, B, E and F affect humans • Types C and D affect animals • Type G is unknown

  5. Health-Related Issues Disease Symptoms • Causes the disease botulism • Results from the ingestion of the neurotoxin (exotoxin) botulin released by C. botulinum while growing on food • Endospores frequently found in honey • Neurotoxins are absorbed into blood stream, affecting the nervous system by preventing the release of aceytlcholine • Symptoms usually begin between 12 and 72 hours after ingestion • Lasts from 1 to 10 days • If not caught early and treated properly, death results • Nausea • Vomiting • Fatigue • Dizziness • Double vision • Drooping eyelids • Slurred speech • Difficulty swallowing • Dryness of skin, mouth, and throat • No fever • Muscle weakness • Flaccid paralysis • Starts with eyes and face, then progresses downward • Eventual asphyxia (death)

  6. Health-Related Issues (cont.) Treatment Types • Antibiotics ineffective, antitoxins more effective • Stop exotoxins in the bloodstream from further affecting the nervous system • Supportive treatment in an intensive care ward • Ventilation may be needed in cases of respiratory failure • Recovery takes weeks because nerve endings must rejuvenate • Food-borne botulism • Most common • Contamination of agricultural products and seafood • Under-processed canned foods or can leakage • Incorrectly home-canned foods • Wound botulism • Occurs when C. botulinum cells affect an open wound • Exotoxinstravel to the bloodstream and then affect the nervous system • Infant botulism • Rare • Symptoms often take weeks to occur • Presents withconstipation, tiredness and inability to feed, followed by respiratory failure

  7. Historical Significance • 1895 – First recognized and isolated by Emile van Ermengem • 1928 – P. Tessemer Snipe and Hermann Sommer able to purify the botulism toxin • 1960s – Alan Scott and Edward Schantz began experimenting with botulism toxin type A (BTX-A) for therapeutic purposes • Cosmetically – used in Botox and other cosmetic formulas to treat frown lines and wrinkles • Therapeutically – muscle pain disorders, upper motor neuron syndrome, blepharospasm, strabismus and hemifacial spasm

  8. Works Cited • Ecolab. Clostridium botulinum. 30 September 2003. 2 February 2011 <http://www.ecolab.com/PublicHealth/Cbotulinum.asp>. • Maricopa Community College. "Chapter 13: Disease Transmission & Pathogenesis." n.d. Biology. 2 February 2011 <http://www.pc.maricopa.edu/Biology/rcotter/BIO%20205/LessonBuilders/Chapter%2013LB/Ch13LessonBuilder_print.html>. • Marler, Bill. "Clostridium botulinum." 23 November 2010. Botulism Blog. 2 February 2011. <http://www.botulismblog.com/botulism-information-1/clostridium-botulinum/>. • Schenectady County Community College. "Clostridium botulinum." n.d. Education that Works. 2 February 2011 <http://www.sunysccc.edu/academic/mst/microbes/36cbotu.htm>. • Wikipedia. 2 February 2011. 2 February 2011 <http://en.wikipedia.org/wiki/Clostridium_botulinum>.

  9. Images Cited • Arsenault, Richard J. "Infant Botulism and Honey." 18 January 2010. NBA Food Advocate. 2 February 2011 <http://www.nbafoodadvocate.com/infant-botulinum-and-honey-2803>. • Cedar Crest College. "Clostridium botulinum." n.d. 2 February 2011 <http://www2.cedarcrest.edu/academic/bio/hale/bioT_EID/lectures/botulinum.html>. • Centers for Disease Control and Prevention's Public Health Image Library. "File:Clostridium botulinum01.png." 23 February 2006. wikipedia.org. 2 February 2011 <http://en.wikipedia.org/wiki/File:Clostridium_botulinum_01.png>. • Keith R. Schneider, Mickey E. Parish, and Renée M. Goodrich. "Clostridium botulinum." 29 October 2010. U. Ill. Food Safety. 2 February 2011 <http://www.extension.org/pages/Clostridium_botulinum>. • Lietz, Jessica. "Clostridium Botulinim Symptoms." 20 November 2009. ehow.com. 2 February 2011 <http://www.ehow.com/facts_5670419_clostridium-botulinim-symptoms.html>. • Maricopa Community College. Chapter 13: Disease Transmission & Pathogenesis. n.d. 2 February 2011 <http://www.pc.maricopa.edu/Biology/rcotter/BIO%20205/LessonBuilders/Chapter%2013LB/Ch13LessonBuilder_print.html>. • Marler, Bill. Clostridium botulinum. 23 November 2010. 2 February 2011 <http://www.botulismblog.com/botulism-information-1/clostridium-botulinum/>. • Matthews, L. "Treating Whiplash with Botox." 17 November 2010. PainNeck.com. 2 February 2011 <http://www.painneck.com/blog/treating-whiplash-botox/>.

  10. Images Cited (cont.) • N.P.K. "Clostridium bolutinum Giant Microbe ." 2 January 2008. Giant Microbes. 2 February 2011 <http://www.giantmicrobes.com/forum/showthread.php?t=6053>. • Schenectady County Community College. Clostridium botulinum. n.d. 2 February 2011 <http://www.sunysccc.edu/academic/mst/microbes/36cbotu.htm>. • Science Channel. "Top 10 Infectious Diseases." 2009 12 December. Science Discovery. 2 February 2011 <http://science.discovery.com/top-ten/2009/infectious-diseases/infectious-diseases-08.html>. • Science Photo Library. "Clostridium botulinum bacteria." 1999. Science Photo Library. 2 February 2011 <http://www.sciencephoto.com/images/download_lo_res.html?id=662201272>. • Science Photo Library. "Clostridium botulinum bacteria." 1999. Science Photo Library. 2 February 2011 <http://www.sciencephoto.com/images/download_lo_res.html?id=662201273>. • Strandwitz, Phil. "Infant Botulism." 17 April 2008. Botulism. 2 February 2011 <http://bioweb.uwlax.edu/bio203/s2008/strandwi_phil/new_page_1.htm>. • Wikimedia Commons. "File:Botulism1and2.JPG." 27 October 2010. Wikimedia Commons. 2 February 2011 <http://commons.wikimedia.org/wiki/File:Botulism1and2.JPG>. • Wikipedia. Botulinum Toxin. 24 January 2011. 2 February 2011 <http://en.wikipedia.org/wiki/Botulinum_toxin>.

More Related