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ANAT3231: Cell Biology Cytoskeleton and its Pathology. Tulin Demir, Lucy Rose Deng, Sarah, Sze-wei and Eilen Saekang. Introduction Microtubules Intermediate Filaments Microfilaments. Intermediate Filaments. Microfilaments
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ANAT3231: Cell Biology Cytoskeleton and its Pathology Tulin Demir, Lucy Rose Deng, Sarah, Sze-wei and Eilen Saekang • Introduction • Microtubules • Intermediate Filaments • Microfilaments Intermediate Filaments • Microfilaments • Microfilaments are essentially polymers of globular protein actin. These long, thin fibres are the thinnest of the three cytoskeletal filaments and are about 8nm in diameter. Formation of microfilaments requires two steps: • Nucleation; and • Elongation • Different actin cross linking proteins form either bundles or networks of actin filaments. • PICTURE/TABLE OF DIFF PROTEINS WITH ACTIN Captions to be set in Times or Times New Roman or equivalent, italic, between 18 and 24 points. Left aligned if it refers to a figure on its left. Caption starts right at the top edge of the picture (graph or photo). Microtubules Current Research Captions to be set in Times or Times New Roman or equivalent, italic, between 18 and 24 points. Right aligned if it refers to a figure on its right. Caption starts right at the top edge of the picture (graph or photo). Captions to be set in Times or Times New Roman or equivalent, italic, between 18 and 24 points. Left aligned if it refers to a figure on its left. Caption starts right at the top edge of the picture (graph or photo). Acknowledgements Captions to be set in Times or Times New Roman or equivalent, italic, 18 to 24 points, to the length of the column in case a figure takes more than 2/3 of column width. Captions to be set in Times or Times New Roman or equivalent, italic, 18 to 24 points, to the length of the column in case a figure takes more than 2/3 of column width.