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Fifth Disease Erythema Infectiosum

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Fifth Disease Erythema Infectiosum

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    1. Fifth Disease Erythema Infectiosum By Heidi Forred

    2. Description Viral illness Parvovirus B19 Symptoms are mild or not evident “Slapped cheek” disease Late winter and early spring

    3. Genome Parvovirus Small round virus Single stranded DNA Lack lipid envelope First Human virus adeno-associated Viruses are not pathogenic

    4. Viral particles at a magnification of x250,000. Scale bar = 100 nm.

    6. History of Fifth Disease Pre vaccine era children commonly contracted. Clinical features have been recognized for two centuries. 1980 linked to Parvovirus B19– the only etiology linked to Erythema infectious.

    7. Signs and Symptoms Low grade fever Headache Mild cold like symptoms Rash: Slapped cheek Adults: joint pain

    9. Contagiousness Before rash Spread by fluids of mouth, nose and throat Large droplets from cough or sneeze. Family members 50% Classmates 60% Pregnant women <5%

    10. Prevention No vaccine Good hygiene

    11. Incubation & Duration Four to twenty-eight days Average of 16 to 17 Rash lasts one to three weeks Adults joint swelling and pain lasts months to years.

    12. Treatment No medication Tylenol (acetaminophen)

    13. Complications Children with weaken immune systems: Can temporarily stop production of red blood cells causing anemia. May effect to supply of oxygen to body tissues. May require blood transfusion and oxygen.

    14. References http://www.ecureme.com/emyhealth/Pediatrics/Erythema_Infectiosum.asp http://cmr.asm.org/cgi/content/full/15/3/485#F1 http://www.aafp.org/afp/991001ap/1455.html http://www.drgreene.com/21_1153.html http://bmj.bmjjournals.com/cgi/content/full/311/7019/1549/F1 http://kidshealth.org/parent/infections/bacterial_viral/fifth.html http://www.virology.net/Big_Virology/BVDNAparvo.html

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