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Transforming Biomedical Science in Connecticut through CICATS Support

Learn about CICATS, a hub at UConn for translational research services including biostatistics, clinical research, and regulatory support. Find resources, tools, and networking opportunities for planning and executing research projects.

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Transforming Biomedical Science in Connecticut through CICATS Support

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  1. TheConnecticutInstituteforClinicalandTranslationalScience(CICATS)TheConnecticutInstituteforClinicalandTranslationalScience(CICATS)

  2. What is CICATS? • The University of Connecticut, in partnership with regional hospitals, state agencies, and community health care organizations, has created the Connecticut Institute for Clinical and Translational Science (CICATS) to transform the way biomedical science is conceived, conducted and disseminated in Connecticut.

  3. The Connecticut Institute for Clinical and Translational Science (CICATS) CICATS Cores Basic Science Education & Training Biostatistics Gateway Biomedical Informatics Pilot Program Community Engagement Regulatory Support Clinical Research Center Tracking & Evaluation

  4. The Connecticut Institute for Clinical and Translational Science (CICATS) CICATS Gateway Investigator Resources

  5. Mission The Gateway is the “front door” for investigators seeking CICATS services and support. We offer referrals, tools, information and programs for investigators initiating and planning clinical and translational research projects. Goals • Inform, educate and engage • Networking and collaboration • Facilitate access to research services

  6. One-stop Shopping

  7. Services & Programs • Research Support • Referral and team development • Listserv, newsletter, website • Seminars and workshops • On-line toolkit • Design Laboratory

  8. Research Toolkit • Research Process Guidance • Electronic tool • Coming Soon – Fall 2011

  9. Research Toolkit

  10. Design Laboratory Feedback for Investigators Planning Clinical and Translational Research Proposals

  11. Networking & Collaboration • Set up your profile and publication list • Search for research partners by expertise • Connect with other investigators

  12. Profiles Research Networking Software

  13. What is Translational Research? Using knowledge from basic science to produce new drugs, treatments, or prevention strategies. Moving treatments, interventions, or “best practices” to the public sector where they may be implemented to improve health. Reduce the gap between discovery and practical application

  14. Translational Research: The Spectrum BENCH PRACTICE BEDSIDE Basic Science Research Preclinical Studies Animal studies Human Clinical Research Controlled observational Studies Phase 3 clinical trials Clinical Practice Delivery of recommended care Identification of new questions T1 Phase 1,2 clinical trials T2 Practice-based Research Phase 3, 4 trials Observational studies Survey Research Guideline Development Meta-analysis Systematic review Adapted from Westfall, J., Mold, J., Fagnan, L. (2007) Practice-Based Research: Blue Highways on the NIH Roadmap, JAMA 297 (4): 403-406. “T3” Dissemination & Implementation

  15. Conclusion The Gateway is and important resource for investigators or trainees seeking CICATS services or trying to navigate the research process.

  16. CICATS Regulatory Regulatory Resources

  17. Mission The overarching purpose of the Regulatory Core is the protection of human subjects and their protected health information (PHI). Goals & Support: • Regulatory support • Regional CICATS IRB • Education & guidance • Clinical research ethics consulting

  18. Conclusion The CICATS Regulatory Core is available for assisting investigators in all matters of regulatory compliance. Contact: Stacey Anderson Phone: 860-679-6213 Email: sanderson@uchc.edu

  19. CICATS Biostatistics Center Biostatistics Services

  20. Mission The Biostatistics Center is the primary resource for providing biostatistical collaboration and support for researchers throughout the UConn Health Center and CICATS partner institutions Goals • Provide support for grant development that leads to externally funded grants and ongoing research collaboration • Consult with researchers to identify best analysis strategies, study design and power analysis • Mentor students and physician-scientists in training • Provide statistical analysis services (fee for service)

  21. Grant Development

  22. Consultations with researchers

  23. Other Services (fee for service) For existing funded projects the Biostatistics Center can provide on a fee for service basis:

  24. Conclusion The CICATS Biostatistics Center is available for assisting investigators in all phases of their research. We look forward to collaborations with researchers. James Grady, DrPH jgrady@uchc.edu

  25. CICATS Clinical Research Center Clinical Research Center (CRC)

  26. Mission The CRC is a comprehensive center providing services in support of high-quality patient-oriented research at the UConn Health Center and affiliated hospitals. Goals • Provide a wide range of administrative, clinical, laboratory and data management services for federally funded, foundation-funded, and industry-supported studies • Ensure the ethical treatment and safety of research subjects and the scientific merit of clinical studies

  27. Clinical Research Center

  28. Clinical Research Center

  29. Clinical Research Center

  30. Clinical Research Center

  31. CICATS Education & Training Master of Science in Clinical & Translational Research Program Anne Kenny, MD, Program Director

  32. Master of Science in Clinical & Translational Research Program Goals • Competitively prepares health care professionals with academic and research skills needed for independent research. • Focus: Preparation of individuals with established, terminal degrees in a health related field (MD, PhD, Pharm.D., DDS or DMD) to conduct independent research in translation of information from the basic sciences to the community as researchers, teachers, public health administrators, clinicians, and industry employees competent to carry out the broad health mission of the State of Connecticut.

  33. THANK YOU…

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