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Happy to answer questions. QUB Staff wellbeing Initiative Dr Anna Gavin Director, N. Ireland Cancer Registry Queen’s University Belfast 29 th January2014. Cancer and How to avoid it. What is Cancer? and How does it start? How many types? Is cancer becoming more common ?
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Happy to answer questions QUB Staff wellbeing Initiative Dr Anna Gavin Director, N. Ireland Cancer Registry Queen’s University Belfast 29th January2014 Cancer and How to avoid it
What is Cancer? and How does it start? • How many types? • Is cancer becoming more common? • Role of Screening for Cancer • What causes Cancer? • What can I do to avoid cancer?
What is Cancer? • Cancer - lot of different types Brain Head & Neck Gut Breast Leukaemia (Blood) Bone Kidney Cervix Prostate Lung Skin
What is Cancer? • Common pathway - DNA in cells
Normal cells • Grow • Limit growth • Repair DNA damage
Cancerous Cells • DNA damage Genetics- tumour suppressor and activation genes- choose your parents well! • Growth unchecked • Tumour • increasingly likely with age
MOST COMMON CANCERS (Males) Cancer incidence, males, Northern Ireland (1993-2011) Cancer deaths , males, UK, 2009
MOST COMMON CANCERS (Females) Cancer deaths, females, UK, 2009 Cancer incidence, females, Northern Ireland (1993-2011)
Why is Cancer More Common? • Ageing population • Control of other diseases e.g. heart disease, infection • Better Diagnosis • Changing Risk Factors
Lifestyle Changes • Lung cancer • 1912 - 12 deaths • 2012 – 1,127 cases
Population more informed More openness regarding cancer
Cancer is increasing due to: • Ageing population • Better diagnosis • Lifestyle - tobacco, diet, less exercise • More awareness of cases in community • Screening
Relative survival of female breast cancer patients diagnosed in 1997-2006 (followed up to the end of 2011) by stage
Figure: Relative survival of female breast cancer patients diagnosed in 1997-2006 (followed up to the end of 2011) by stage Screening and Cancer 1. Early Stage Disease – easier to treat and better survival – GoalREDUCE DEATHS 2. Some Screening Tests – pick up pre-cancer - Cervical Smear - Bowel Cancer Screening 3, Breast screening - picks up existing cancer
Debate What are the harms and benefits of screening Mortality reduction Over Diagnosis
Screening Debate Breast 3 over diagnosed : 1 death prevented Prostate 48 over diagnosed – 1 death prevented Colorectal/Bowel and Cervix – pick up and treat early disease so preventing cancer
Estimated Percentage of Cancer Deaths Attributed to Various Factors
Tobacco Related Cancers • Oral • Lung • Larynx • Stomach • Oesophageal • Pancreas • Cervix • Kidney • Bladder
Overweight • Breast over age 50 • Uterus • Kidney • bowel
Waist tape measurement • Normal limits • MEN <37” • WOMEN <31.5”
Health Eating Can Help Prevent:- • Heart Disease • Constipation • Obesity • Bowel Trouble • Tooth Decay • High Blood Pressure • Diabetes • Some Cancers • Musculo-skeletal Problems
Weight Control • Use a smaller plate • Expect results over a long period • Eat smaller meals more often • Change cooking method - grill • Don’t crash diet • Increase exercise
Be Safe • Avoid sunburn • NO sunbeds • Avoid 11am – 3pm • Use shade • Cover up – including hat and sunglasses • Sunscreen – 15 Sun Protection Factor (SPF) • Go early if concerned
Avoid Cancer • Don’t Smoke • Eat 5 or more Fruit/Vegetables per day • Exercise • Avoid sunbeds and sunburn • Maintain sensible weight
Pick up Early • Screening when invited – breast, cervix, bowel • Be aware of changes – cough, bowel, skin, weight • Seek medical advice early
Thanks To: N I C Council & Steering Group R Patients ORECNI PHA GAIN Trusts CRUK QUB BSO HSCB Cancer Staff Clinicians Focus Prostate Cancer UK R&D DHSSPSNI Macmillan NISRA Office for Research Ethics Committees Northern Ireland (ORECNI)