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Centrifugal Separator for Pharmaceutical and Biotechnology Applications

Centrifugal Separator for Pharmaceutical and Biotechnology Applications. Tomoe Engineering Co., Ltd. Outline. Tomoe Engineering Co., Ltd. Concluded a technical assistance agreement with Sharples Corp., U.S., and initiated the manufacture and sale of centrifuge in 1950.

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Centrifugal Separator for Pharmaceutical and Biotechnology Applications

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  1. Centrifugal Separator for Pharmaceutical and Biotechnology Applications Tomoe Engineering Co., Ltd.

  2. Outline • Tomoe Engineering Co., Ltd. Concluded a technical assistance agreement with Sharples Corp., U.S., and initiated the manufacture and sale of centrifuge in 1950. • Alfa Laval purchased Sharples Corp. in 1990 and then Tomoe and Alfa Laval kept cooperated relationship.

  3. Characteristics of Tomo-e Tubular Centrifuge • High G-Force : 20000G • GMPApply : U.S.FDA& European Spec. • SIPApply ：121℃ Spec. • Many Machine Line-up ：Several Capacity

  4. Performance, ASM260 Typical performance of ASM260 • Colitis germs ：100L/Hr • Colitis germs (mash) ：50L/Hr • Lactic acid bacilli ：70L/Hr • Vaccine ：50L/Hr • Cryo ：200L/Hr • Yeast Cell ：500L/Hr

  5. Laboratory Use, T-1 • Bowl Capacity ：0.27L • Max. G-Force ：62000G • Elec. Power ：0.1Kw • Dimension ：430×250×800

  6. Pilot Plant Use, ASM100 • Bowl Capacity ：2.5L • Max. G-Force ：20000G • Elec. Power ：1.5Kw • Dimension：760×400×1150

  7. Middle Size, ASM160 • Bowl Capacity ：5.5L • Max. G-Force ：17000G • Elec. Power ：2.2Kw • Dimension：780×870×1500

  8. Structure of ASM160

  9. ASM160 PL VBNF

  10. Large Centrifuge, ASM260 • Bowl Capacity：7.8L • Max. G-Force：20000G • Elec. Power ：7.5Kw • Dimension ：1010×870×1630

  11. ASM260VBNF

  12. Another Type and Specifications • Tomo-e Tubular Centrifuge • Type UnitT-1 ASM100 ASM160 ASM260 ASM460 ASM660 • RPM rpm 50,000 19,000 17,000 17,000 15,000 12,200 • G-Force G 62,000 20,000 17,000 20,000 20,000 15,000 • Bowl Dimension mm 44φ×201 95φ×457 105φ×720 124φ×720 160φ×720 190φ×1328 • Bowl Capacity L 0.27 2.5 5.47 7.8 13.2 33.7 • Elec. Power Kw 0.1 1.5 3.7 7.5 18.5 37 • Typical Capacity L/Hr 5 30 60 100 150 300

  13. Instruction for Drag Bushing

  14. Installation for Spindle/Bowl

  15. Installation for Bowl Ass’y

  16. Installation for Idlar Ass’y & Bearing Ass’y

  17. Installation for Bearing Ass’y No.1

  18. Installation for Bearing Ass’y No.2

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