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Mammalian Sweet Taste Reception : Tas1R2. Nadia Moosvi . Background. T1R2 and T1R3 are metabatrophic, glutamate receptor proteins Tas1R2 and Tas1R3 genes confirmed to function in sweet taste reception by knock out experiments Differences in human and mouse/rat sweet taste . Chimpanzee.
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Mammalian Sweet Taste Reception : Tas1R2 Nadia Moosvi
Background • T1R2 and T1R3 are metabatrophic, glutamate receptor proteins • Tas1R2 and Tas1R3 genes confirmed to function in sweet taste reception by knock out experiments • Differences in human and mouse/rat sweet taste
Chimpanzee Opossum Rabbit Orangutan Pig Platypus Mouse Rat Human Human Rhesus Macaque Dog Dog Cow Horse Phylogenetic Tree Herbivore Omnivore Carnivore
Alignment of Crucial Regions Rhesus Macaque Rhesus Macaque Rhesus Macaque Human Human Human Mouse Mouse Mouse Rat Rat Rat
Other Considerations • Not enough information on carnivores • Diverse diets included in this analysis • Great diversity within species: several polymorphisms for mouse, rat, and human genomes