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NextPharma Technologies Experts in the production of Pellets. What We Can Do For You. Formulation and Development of new products:
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NextPharma Technologies Experts in the production of Pellets
What We Can Do For You Formulation and Development of new products: Our Development Department is specialized in the development and formulation of new pellets and granule products. Its laboratory is specially equipped with the necessary technologies for this task. Production: The production of aqueous and organic granules, extrudates and pellets, coating, tabletting and capsule filling of granules and pellets.
What We Can Do For You Quality Control and Contract Analysis Modern and highly qualified laboratory for the analysis of all types of products (our specialist for the analysis of pellets), stability testing and development of analytical method.
Technologies Granulation: Aqueous and organic granulation (high shear mixer and fluid bed granulation) Extrusion / Spheronisation: For the production of homogeneous and organic extrudates and pellets Coating: Aqueous or organic coating of granules and pellets Layering Production of heterogeneous pellets using suspension-layering
Options for characteristics of produced pellets • Controlled Release • Can be achieved through: • Coating with special films (gastro resistant or pH independent diffusion film) • Difussion from Matrix-pellets Odour or Taste Masking By coating the pellets with specific films in order to mask the unsuitable odour or taste Colouring / Flavouring To enhance the patient compliance / acceptance by coating the pellets with accordingly special layers
Spheroniser: Ring die press (extruder): High shear mixer: Spheronisation Extrusion Blending & moistening extrudate moist pellets Production of pellets with extrusion / spheronisation Fluid bed dryer: Kugelcoater: Coating Drying
Extrusion / Spheronisation Equipment Blending & Moisting: Diosna P 400
Extrusion / Spheronisation Equipment Extrusion: Schlüter PP-127
Extrusion / Spheronisation Equipment Spheronisation: Schlüter RM-700
Extrusion / Spheronisation Equipment Fluid Bed Drying: Hüttlin HD 400
Layers with active substance Spraying nozzle Production of pellets with suspension layering Non-pareil Layers containing the active are sprayed onto non-pareils in a Kugelcoater (Bowl-coater)
Coating and Layering Equipment Fluid Bed Coater and Granulator: Hüttlin HKC 300-TJ