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Siegfried Schrei Siemens MI Applications

The BRAINs Orientation. Siegfried Schrei Siemens MI Applications. In addition, the anterior commisure and posterior commisure are used for the horizontal orientation in the sagittal plane.

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Siegfried Schrei Siemens MI Applications

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  1. The BRAINs Orientation Siegfried Schrei Siemens MI Applications

  2. In addition, the anterior commisureand posterior commisure are used for the horizontal orientation in the sagittal plane. The standard orientation calls for lining up the interhemispheric fissure. This sets the alignment in the coronal and axial planes. Manual Orientation

  3. Where are the Anterior and Posterior commissure? Positioning of Vertical AC and PC Lines

  4. Where are the Anterior and Posterior commissure? Positioning of Vertical AC and PC Lines (Spect fix distance)

  5. Horizontal AC to PC line Horizontal AC - PC Line.

  6. Rotate Brain to Anterior and Posterior commissure axis Horizontal AC - PC Line.

  7. Size Alignments

  8. Talairach Atlas in Neurogam

  9. The mapped Brain

  10. Where are the Anterior and Posterior commissure? The perfect alignment: Reperate right and left hemisphere AC – PC line for correct Axial planes

  11. MRI Image or CT images are co registered to the manually reoriented SPECT or PET image by use E.Soft Image Fusion or Syngo 3D Image registration. Manually aligned by visual matching, surface matching or use of anatomical land marks. By far the preferable method is the fully automated alignment based on Mutual Information co registration. When fitting is complete each MRI image is resampled to the SPECT or PET orientation and resolution (128 x 128 Matrix, ca 5 mm cubic voxels). Point to point correspondence with any given set of coordinates referring to the same point in all of the images Coregistration Modalities

  12. Define a Talairach-based atlas for the each scan individually (MRI more easy compared to SPECT) Landmarks used Right-most extent of the brain Left-most extent of the brain Anterior-most extent of the brain Posterior-most extent of the brain Superior-most extent of the brain Inferior-most extent of the temporal lobe AC and PC locations Talairach Bounds

  13. Talairach Atlas Talairach atlas coordinate system Resampled image with overlaid Talairach coordinate system

  14. Talairach Bounds

  15. Talairach levels of definition

  16. Talairach Atlas warped onto current brain. Various "boxes" assigned to various regions Measure volumes of labelled brain regions Talairach Regions Talairach Boxes Cyan - Frontal Blue - Temporal Green -Parietal Red - Occipital Pink - Cerebellum Yellow - Subcortical Gray - Brainstem

  17. Talairach vs. Brodmann

  18. The matched regions

  19. T1 and T2 ImagesTissue Classified Images

  20. Cortical Surface

  21. Currently defines the following regions Caudate Putamen Thalamus Cerebellum Cerebellar lobes (warping) Hippocampus (requires editing) Globus Pallidus (requires editing) In the near future will use a warped method for all structures – more valid, less editing Will also add nucleus accumbens and amygdala Neural Network

  22. Neural Network Inputs

  23. Artifical Neural Networks

  24. Cerebellum Lobes Cerebellar Lobe Volumes: Uses landmark-based warp for semiautomated measurement of Lobes I through V (anterior lobe), Lobe VI and Crus I of VIIA (superior posterior lobe), Crus II of VIIA through Lobe X (inferior posterior lobe), and the central white matter and output nuclei(corpus medullare).

  25. What about the cerebellum? Not included in Talairach Atlas Used for automated gross regional measures Provides a coordinate system for structure probability Talairach Atlas II

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