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WARM UP. NOTES CH 29. Lymphatic System and Immunity Intro. PARTS:. Lymph, lymphocytes, lymph nodes, spleen, thymus, tonsils. FUNCTIONS:. FLUID BALANCE FAT ABSORPTION DEFENSE ** * filter microorganisms in lymph nodes and spleen * destroy micro. in tissues. LYMPHOCYTES.
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NOTES CH 29 Lymphatic System and Immunity Intro
PARTS: Lymph, lymphocytes, lymph nodes, spleen, thymus, tonsils
FUNCTIONS: • FLUID BALANCE • FAT ABSORPTION • DEFENSE ** * filter microorganisms in lymph nodes and spleen * destroy micro. in tissues
LYMPHOCYTES Cells that destroy microbes
LYMPH • Clear fluid that is in tissues after leaving the blood • Made of ions, water, nutrients, gases, hormones, wastes • Circulates through lymph vessels and into nearest lymph node
LYMPH NODE About small seed to almond size Lymph passes through here before returning to blood • Stimulates lymphocytes to divide and go into bloodstream • Destroy microorganism there
3 main places of nodes • INGUINAL • AXILLARY • CERVICAL
TONSILS • Areas in the mouth that collect and destroy microbes • Palantine – sides • Adenoid – back top of throat • Lingual – back of tongue
SPLEEN • Size of fist, let upper side FUNCTION: • Filters blood – cells detect microbes or old rbc in blood and destroy • Stores extra blood for emergencies • Makes lymphocytes
THYMUS • Lower neck area ( after 60 decrease in size) FUNCTION: 1. Produce lymphocytes
NOTES Ch 29 Immunity
IMMUNE SYSTEM PARTS: white blood cells, antibodies FUNCTION: to destroy microbes in tissues and protect body from disease
LEUKOCYTES – white blood cells Leave the blood vessels and go into infected area to destroy microbe TYPES: • neutrophils • macrophages • lymphocytes
NEUTROPHILS • 1st to enter infected area • Die after killing a microbe • Phagocytosis – engulfing the microbe or cell to destroy it PUS – fluid, dead neutrophils, bacteria, dead cells
MACROPHAGE • 2nd to enter an infected area • Can digest more and live longer • Can wait in uninfected tissue
B CELLS • Secrete antibodies T CELLS
IMMUNITY Ability to resist damage from foreign substances
ANTIGEN Foreign substance in the body EX: virus, bacteria, allergen (pollen, animal hair, foods, etc.) ANTIBODY Protein that destroys a specific antigen
INNATE Body born with ability to recognize and destroy foreign molecules ADAPTIVE Body learns to recognize and destroy (each time exposed, destroy better) 2 TYPES
INNATE Protections such as Skin, mucus, tears, saliva Chemicals: Histamine, lysozyme, prostoglandins, leukotrienes These promote inflammation and cause white blood cells to rush there
2 TYPES OF ADAPTIVE IMMUNITY • NATURAL a. Passive – mother to child (umbilical cord or milk) b. Active – natural exposure (exposed to a virus, etc.)
ARTIFICIAL a. Passive – antibodies placed into person (from another organism) * won’t last long (antiserum is an example)
Active – antigen deliberately introduced into individ. to stimulate their immune system EX: VACCINATION * dead organism or live altered one (produces no symptoms)
DTP Diptheria Tetanus Pertussis (whooping cough) MMR Mumps Measles Rubella 2 main types of vaccinations
HOW IMMUNITY WORKS Every cell has surface marker on the cell membrane. When body does not recognize these markers, it will respond to it.
THE RESPONSE: • B cell exposed to antigen • Binds to it • B cell starts to divide to form 1) memory B cells 2) plasma cells
PLASMA CELLS Produce antibodies – takes 3-14 days to make enough to destroy it Antigen can cause symptoms in the meantime MEMORY B CELLS When exposed to antigen already in the body, these divide and from plasma cells which make the antibodies fast No time for symptoms to develop