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DIGESTIVE GLANDS. - CHA -. THE LIVER THE GREATEST MEASUREMENT OF ORGAN IN HUMAN ( 1,5 KG ), CONSIST OF 4 LOBUS. - CAPSUL CONSIST OF CONNECTIVE TISSUE, NAMELY IS GLISSON’S CAPSUL. THE LIVER COMPOSED OF LOBULES WHICH
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DIGESTIVE GLANDS - CHA -
THE LIVER • THE GREATEST MEASUREMENT OF ORGAN IN • HUMAN ( 1,5 KG ), CONSIST OF 4 LOBUS. • - CAPSUL CONSIST OF CONNECTIVE TISSUE, • NAMELY IS GLISSON’S CAPSUL. • THE LIVER COMPOSED OF LOBULES WHICH • ARE SEPARATED FROM EACH OTHER BY A • LAYER OF CONNECTIVE TISSUE, CALLED • HEPATIC LOBULS. • - HILLUS OF LIVER NAMELY IS PORTAL • HEPATIS, WHICH IN THIS PLACE, BLOOD • VESSELS, CONNECTIVE TISSUE AND BILLIARY • DUCT ARE ENTERING TO THE LIVER.
THE LOBULES OF LIVER ARE SEPARATED BY • CONNECTIVE TISSUE AND BLOOD VESSELS. • THE CORNER OF THREE LOBULS CREATE PORTAL • AREA = PORTAL CANAL. • THE CONTAIN OF PORTAL CANAL : • 1. INTERLOBULARIES VEIN IS BRANCH OF • PORTA VEIN. • 2. INTERLOBULARIES ARTERI IS BRANCH OF • HEPATICA ARTERI • 3. INTERLOBULARIES DUCT IS BILLIARY DUCT • 4. ANOTHER COMPONENTS LIKE LYMPHATIC • VESSELS AND NERVE FIBERS. • 1,2 AND 3 ARE CALLED PORTAL TRIAD
LIVER IS COMPOSED OF : • LIVER PARENCHYM, CONSIST OF LAMINA • HEPATIS ( HEPATOCYTE CELLS PLAQUE ), WHICH RADIER ARRANGE WITH CENTRALIS VEIN AS A AXIS. • 2. SINUSOID, A SPACE BETWEEN LAMINA HEPATIS, WHICH THE WALL CONSIST OF : • - ENDOTHEL • - KUPFFER CELLS CELLS WHICH HAVE • PHAGOCYTIC CHARACTER. • - SUPPORTING TISSUE, WHICH CONSIST OF • RETICULER FIBERS.
BLOOD VESSEL OF THE LIVER : • PORTA VEIN : • FUNCTIONAL BLOOD FROM INTESTINE AND LIEN, AND THEN DISTRIBUTE TO INTERLOBULARIES VEIN SINUSSOID CENTRALIS VEIN SUBLOBULARIS VEIN HEPATIVA VEIN CAVA INFERIOR VEIN. • HEPATICA ARTERI • NUTRITIF, BLOOD DISTRIBUTE TO INTERLOBULARIS ARTERI A PART OF THE PORTAL CANAL AND ANOTHER TO THE PERILOBULAR AREA.
LIMPHATIC VESSEL IN LIVER : • CREATE NETWORK AROUND GLISSON • CAPSULE, INTERLOBULARIS SEPTUM, AROUND • BLOOD VESSELS AND BILLIARY DUCT. • IN LOBULUS THERE ISN’T LIMPHATIC VESSEL. • LYMPHATIC LIQUID BE GATHERED IN SPACE • OF DISSE SPACE OF MALL LYMPHATIC • VESSELS IN PORTAL AREA.
LIVER FUNCTIONS : • PROTEIN SYNTHESIS • EMPEDU SECRETION • METABOLIT DEPO • METABOLISM • DETOXICATION • 6. PHAGOCYTOSIS, ETC.
GALL BLADDER • IS A HOLLOW, PEAR- SHAPE ORGAN, CONSIST OF • FUNDUS, CORPUS AND COLLUM. • MUCOSA • - MUCOSA LAYER PRESENT FOLDS THAT ARE • PARTICULARLY EVIDENT IN THE EMPTY • BLADDER. • - A MUCOSA LAYER COMPOSED OF COLUMNAR • EPITHELIUM AND LAMINA PROPRIA. • - DIVERTICULUM (+) • - THERE IS NOT MUSCULARIS MUCOSAE
A LAYER OF SMOOTH MUSCLE • IS A THICK SMOOTH MUSCLE TISSUE, WHICH • HAVE TWO DIRECTIONS : • - INNER : LONGITUDINAL • - OUTER : CIRCULAR • A SEROSA MEMBRAN / ADVENTITIA • SUPERFICIAL LAYER IS COMPOSED OF DENSE • CONNECTIVE TISSUE WITH COLLAGEN • FIBERS, BINDS TO CAPSULA GLISSON IN • SOME PLACES, AT ANOTHER PLACES IS LINED • BY PERITONEUM.
FUNCTION : • - STORE BILE AND CONCENTRATE IT BY • REABSORBING ITS WATER. • THE WATER IS ABSORBED BY EPITHEL TISSUE. • EXTRA HEPATIC DUCT • 1. HEPATIC DUCT • TO DISTRIBUTE BILE FROM LIVER TO • GALLBLADDER. • CYSTIC DUCT • TO DISTRIBUTE BILE FROM HEPATIC DUCT TO GALLBLADDER
COMMON BILE DUCT = CHOLEDOCHUS DUCT • TO DISTRIBUTE BILE FROM HEPATIC DUCT AND CYSTIC DUCT TO DEUDENUM. • HISTOLOGY STRUCTURES : • MUCOUS : - SIMPLE COLUMNAR EPITHELIUM • - AT COLLUM GALLBLADDER, PRESENT • FOLDS, AT DUCTUS CYSTICUS THERE • IS SPINCTER, NAMELY HEISTER • SPINCTER. • MUSCULARIS : NOT SO CLEAR.
SALIVARY GLANDS • INTRINSIC GLANDS ( MINOR ) LABIALIS GLAND, • BUCCALIS GLAND, PALATINAE GLAND. • EXTRINSIC ( MAYOR ) : • - PAROTIS GLAND • - SUBMAXILLARIS / SUBMANDIBULARIS GLAND • - SUBLINGUALIS GLAND • FUNCTION : SALIVARY SECRETION
GENERAL STRUCTURE OF SALIVARY GLANDS : • COMPOSED OF : • PARENCHYM : GLANDS ACINI • STROMA : CONNECTIVE TISSUE • FRAMEWORK • THERE ARE THREE KINDS OF ACINI : - SEROUS • - MUCOUS • - MIX
SEROUS ACINI EPITHEL : SIMPLE COLUMNAR, LIKE PYRAMID SHAPE AND HAVE A NARROW LUMEN AND THE BORDER OF EACH CELL IS NOT CLEAR. CYTOPLASM : HAVE ZYMOGEN GRANULES COLOR : IS DARKER THAN MUCOUS ACINI AND HAVE MYOEPITHEL CELLS ( BASKET CELLS ) SUPPORT SECRETION DISCHARGE.
MUCOUS ACINI EPITHEL : SIMPLE SQUAMOUS OR LOW CUBOID, THE BORDER OF EACH CELL IS NOT CLEAR, LUMEN IS WIDE AND NUCLEAR SHAPE IS FLAT. CYTOPLASM : FILL WITH VACUOLA MUCIGEN AND WITH H.E STAIN HAVE PALE COLOR. MIXED ACINI THERE SROUS ACINI THAT HOLD MUCOUS ALVEOLI SEROUS ALVEOLI LIKE “BULAN SABIT”, NAMELY IS DEMILUNE OF GIANUZZI.
EXIT DUCT : • INTERCALATED DUCT : • - INTRA LOBULAR • - SIMPLE SQUAMOUS OR LOW CUBOID • EPITHELIUM • STRIATED DUCT • - INTRA LOBULAR • - SIMPLE COLUMNAR EPITHELIUM • INTERLOBULAR DUCT • - SIMPLE COLUMNAR OR PSEUDOSTRATIFIED • EPITHELIUM • 4. MAIN DUCT : PSEUDOSTRATIFIED EPITHELIUM
PAROTIS GLAND • IS THE GREATEST SALIVARY GLAND. • HAVE A CAPSUL, WHICH HAVE BRANCH THAT • DIVIDED BECOME INTERLOBARIS AND • INTERLOBULARIS SEPTA. • ACINUS : PURE SEROUS • EXIT MAIN DUCT IS CALLED DUCTUS STENONI. • SUBMAXILLARIS / SUBMANDIBULARIS GLAND • IS A MIXED GLAND, THERE ARE SEOUS AND • MUCOUS ACINI, WHICH THE NUMBER OF SEROUS • ACINI IS MORE THAN MUCOUS ACINI.
THERE ARE DEMILUNE OF GIANUZZI. • THE EXIT MAIN DUCT, NAMELY IS DUCTUS • WHARTONI. • SUBLINGUALIS • IS THE SMALLEST OF SALIVARY GLAND AND • ALSO MIXED GLAND. • THE NUMBER OF MUCOUS ACINI IS MORE • THAN SEROUS ACINI. • DEMILUNE OF GIANUZZI (+) • CAPSUL IS NOT CLEAR AND WITHOUT SEPTA. • - IS DIFFICULT TO FIND INTRALOBULAR DUCT.
INTERCALATED DUCT KEL. PAROTIS SRIATED DUCT
ACINI MUCOUS KEL. SUBMAXILLARIS
Demilune dari Gianuzzi Kel. Sublingualis Striated duct
PANCREAS IS A DOUBLE TUBULOALVEOLAR GLAND WHICH HAVE EXOCRINE CHARACTER. THERE ARE SPECIAL STRUCTURES LANGERHANS ISLAND, WHICH HAVE ENDOCRINE CHARACTER. HORMON, THAT PRODUCED BY LANGERHANS ISLAND : - INSULIN, BY b CELLS ( CHANGE GLUCOSA TO BECOME GLYCOGEN ) - GLUCAGON, BY A CELLS.
THE CHARACTER IS PURE SEROUS, THERE ARE CENTRO-ACINAR CELLS, WHICH IS PROLONGATION OF INTERCALATED DUCT. THERE IS NO STRIATED DUCT AND THE MAIN DUCT NAMELY IS WIRSUNGI DUCT.
pancreas Cell centroacinar