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Marshall Lenko Presents. A Douglas Rust Production. Cirrhosis. What is Cirrhosis?. Condition in which liver tissue has been progressively destroyed by infection, poison, or other disease Normal liver tissue is replaced by scarring
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A Douglas Rust Production Cirrhosis
What is Cirrhosis? • Condition in which liver tissue has been progressively destroyed by infection, poison, or other disease • Normal liver tissue is replaced by scarring • Liver may initially grow in size to compensate for liver cells not being able to perform their normal functions • Overtime with more scarring the liver becomes smaller • This scar tissue blocks blood flow through the liver
What Causes Cirrhosis? • Cirrhosis occurs after years of heavy drinking • Developes in as many as 15% of alcoholics • Cryptogenic cirrhosis, the final stage of chronic liver disease, is caused by Hepatitis B or C • Primary Biliary cirrhosis is caused by chronic inflammation and scarring of the microscopic bile ducts within the liver • Some other causes can be reactions to drugs, congestive heart failure, certain parasites, and malnutrition
Weight loss Nausea and vomiting General fatigue Jaundice Abdominal Pain Intestinal Bleeding Swelling of Legs Loss of Appetite Loss of interest in sex Small, red spider-like blood vessels under skin Easy Bruising Small Collections of fat around the eyes Symptoms of Cirrhosis
What Happens to People with Cirrhosis? • Liver can’t process blood and remove breakdown products properly, affecting the brain • Blood levels of these substances can cause tremor of hands, mental confusion, and even a coma • As damage progresses, fluid collects in the legs and abdomen, this leads to bacterial peritonitis (a serious infection) • Blood backs up into the spleen causing it to enlarge
Treatment • The damage caused by cirrhosis is irreversible, there is no real cure • A healthy diet is the most important thing at every stage of cirrhosis • Giving up alcohol will not reverse damage but the person will feel better and may even live longer • In severe cases of cirrhosis, patients have had liver transplants in the recent years • Experts report that people who have had liver transplants now survive for five or more years
Other Facts • Eleventh leading cause of death in the US • Just over 9 people per 100,000 die of cirrhosis each year • Cirrhosis caused by alcoholism usually occurs after 10-15 years of heavy drinking • 10-20% of heavy drinkers develope cirrhosis • 1 in 4 people with chronic hepatitis C develope cirrhosis
Works Cited Information Lawson, David. Mayo Clinic Family Health Book. New York: William Morrow and Company, Inc. Bunch, Bryan.(2003) Cirrhosis. “Diseases” (Vol. 2 pp75-78) Dunbury: Scientific Publishing, Inc. Runyon, B. (2008). Cirrhosis. Retrieved May 14th, 2009, from http://digestive.niddk.nih.gov/ddiseases/pubs/cirrhosis/ Worman, 4. (2000). Cirrhosis. Retrieved May 14th, 2009, from http://www.cumc.columbia.edu/dept/gi/cirrhosis.html American Liver Foundation. (2007). Cirrhosis. Retrieved May 14th, 2009, from http://www.liverfoundation.org/education/info/cirrhosis/
Works Cited cont. Pictures http://www.hivandhepatitis.com/2006icr/ddw/docs/060906_c.html http://www.montana.edu/wwwai/imsd/alcohol/Vanessa/vwliver_files/image004.jpg http://www.hivandhepatitis.com/0_images_2008/fatty2.gif