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Contrast 2. Pharmacological agents. Pharmacological agents. Hyoscine –N- butyle bromide( Buscopan ) Adult dose 20mg I/V It inhibit intestinal motility and gastric secretion Advantages. Immediate action,short duration of action and it is not expensive
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Contrast 2 Pharmacological agents
Pharmacological agents • Hyoscine –N-butyle bromide(Buscopan) • Adult dose 20mg I/V • It inhibit intestinal motility and gastric secretion • Advantages. Immediate action,short duration of action and it is not expensive • Disadvantages. Blurring of vision,drymouth,tachycardiaand urinary retention. • Contraindications.close angle glaucoma,myastheniagravis,pylorisstenosis etc • glucogon can be used in these situations
Glucogon • Adult dose. .3—1mg • Childern dose ,5—1microgram/kg • Advantages.more potent smooth muscle relaxant than glucogan,,short duration of action and it do not interfer with ttransit time of bowel • Disadvantages.hypersensetivityteaction is possible,long onset of action and expensive
Contraindication of glucogan • Adrenal tumors.glucogan can cause sudden hypertension.if hypertension occure,phentolamine can be used for treatment • Endocrine tumors of pancrease
Meticlopramide(maxolon) • It stimulate gastric empying and and short small intestinal transit. • Adult dose.20mg oral or i/v • Advantages it is antiemitic and enhance transit of barium during follow through examination • Disadvantages.extrapyramidal side effects.theseoccure more likely in childern