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Anatomy and Physiology of Balance. Vestibular Hair Cells. Type I (aka inner) Type II (aka outer) With Kinocilium. The Semicircular Canals. posterior canal shares plane with contralateral anterior canal. horizontal canals share plane. Stimulated by Angular Acceleration.
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Vestibular Hair Cells • Type I (aka inner) • Type II (aka outer) With Kinocilium
The Semicircular Canals • posterior canal shares plane with contralateral anterior canal. • horizontal canals share plane.
Stimulated by Angular Acceleration • greatest when fulcrum is within head • induces relative motion of endolymph • crista is displaced by fluid motion
Responses of the Cristae • All kinocilia are oriented in the same direction • Crista in each pair of canals respond inversely to each other
The Otolithic Organs Saccule: roughly vertical orientation, responds to acceleration components within saggital plane Utricle: horizontal (+ 30 deg.) orientation
Excitation Patterns in the Utricle STRIOLA Anterior Posterior Medial
Vestibular Portion of C.N. VIII • superior division: utricle, anterior part of saccule, and horiz & anterior canals • inferior division: posterior part of saccule, and posterior canal • to vestibular nuclei • to cerebellum
Vestibulocochlear Nerve • Exits temporal bone near its medial edge. • Enters lateral face of brainstem at the level of the lower pons. • Synapsing in (Cochlear and) Vestibular Nuclei
Responses of Vestibular Neurons: • To changes in acceleration, but onset and fade slowly • For most normal head movements firing rates are in phase with head VELOCITY.
Other inputs to vestibular nuclei: • Cerebellum: primarily inhibitory • Spinal cord • Pontine reticular formation • Contralateral vestibular nuclei
From the Vestibular Nuclei: • Vestibulo-Oculomotor Pathways: • Direct: to oculomotor nuclei. • Indirect: via reticular formation to oculomotor nuclei (III IV and VI) • Vestibulo-Spinal Pathways: • Lateral V-S-throughout spinal cord • Medial V-S-cervical & thoracic • Reticulospinal tract-via brainstem reticular formation
In the brainstem • Vestibular inputs undergo integration • Integrated signal is combined with original (velocity driven) signal • Processing to reset spatial map for eye musculature
Ocular Musculature Superior Rectus (SR) Inferior Rectus (IR) Lateral Rectus (LR) Medial Rectus (MR) Superior Oblique (SO) Inferior Oblique (IO)
Superior Rectus Superior Oblique Midline Lateral Rectus Medial Rectus Inferior Rectus Inferior Oblique
The Oculomotor Cranial Nerves • III the oculomotor • IV the trochlear • VI the abducens
III (Oculomotor) innervates: 1) Medial rectus 2) Superior rectus 3) Inferior rectus 4) Inferior oblique Levator palpebrae sup Pupillary sphincter Ciliary muscle
IV (Trochlear) innervates: • Superior oblique
VI (Abducens) innervates • Lateral rectus.
Proprioceptive info from eye muscles • comes through Trigeminal nerve.
Eye Movements • Saccades—rapid shift in gaze • Pursuit—stabilize image of moving object • Fixation—stabilize image of still object • VOR—stabilize image during head motion • OKN—backup for when VOR decays to cont’d head rotation • Vergent movements—change depth of focus
Saccades Pause cells inhibit Burst Neurons which stimulate: III & VI (horizontal) or III & IV (vertical)
Compare, Select & Combine Senses Visual System Vestibular System Somato- Sensation SENSORY INPUTSVisionVestibularSomatosensory
SOMATOSENSORY RECEPTORS Compare, Select & Combine Senses Somato- Sensation JointsPositionKinesthesia MusclesLengthTension SkinTouchPressure
VISUAL RECEPTORS Compare, Select & Combine Senses Visual System CentralOrientation Navigation PeripheralMotion-sensitive Body-sway
VESTIBULAR RECEPTORS Compare, Select & Combine Senses Vestibular System Semi-circular canalsOrientation Navigation Utricle & SacculeHorizontal & vertical acceleration & deceleration
SENSORY ORGANIZATION Determination of BodyPosition Compare, Select & Combine Senses Visual Vestibular Somatosensory • Processingof inputs from the periphery Selection based on • Availability Accuracy • Valuefor the task at hand