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Endocrine System

Endocrine System. Endocrine: Ductless Glands that secret hormones into the body. Functions. Maintains homeostasis Long-term control using chemical signals. The endocrine system works in parallel with the nervous system to control growth and maturation along with homeostasis.

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Endocrine System

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  1. Endocrine System

  2. Endocrine: Ductless Glands that secret hormones into the body

  3. Functions • Maintains homeostasis • Long-term control using chemical signals. • The endocrine system works in parallel with the nervous system to control growth and maturation along with homeostasis.

  4. HormonesChemical Messengers

  5. Delivery System

  6. Endocrine Gland Stimuli

  7. Grouped into three classes based on their structure: • Steroids • Peptides • Amines

  8. Steroids • Made of Lipids derived from cholesterol. • 2. Steroid hormones are secreted by the gonads, adrenal cortex, and placenta. Examples: Testosterone Progesterone Aldosterone

  9. Peptides • Short chains of Amino Acids • Most hormones are peptides • Processed by the E.R. and Golgi Apparatus • Stored in vesicles- released when needed

  10. Amines • A modified amino acid- tyrosine • Stored in the cytoplasm • Example: epinephrine

  11. Lipid Soluble: Such as Steroids

  12. Hormones Regulate Gene Expression First Messenger   Second Messenger Regulates Gene Expression

  13. Water Soluble- 2 messenger mechanism

  14. Hypothalamus: Master Gland

  15. Posterior Pituitary • storage of hormones produced in hypothalamus • Release upon neural impulse • Diabetes insipidus- ADH deficiency – large amount of urine output

  16. Anterior Pituitary Gland • Produce and storage of hormones • Production regulated by Hypothalamic hormones- • GHRH, GHIH, TRH, CRH, GnRH, PIH

  17. Regulation of Ant Pit. Hormones

  18. Thyroid Hormone

  19. Negative Feedback Regulation

  20. Insulin and Glucagon-Regulation of Blood Sugar Levels

  21. Regulation of Blood Volume and Pressure Antidiuretic hormone (ADH) is a chemical messenger molecule which is made in the hypothalamus and stored in the posterior pituitary gland. When osmoreceptors in the posterior pituitary sense blood which is too concentrated, ADH is released to increase water reabsorption by the kidneys. Review the maintenance of water and salt balance by means of antidiuretic hormone (ADH) and aldosterone on pages 318 and 323, Construct feedback loop diagrams which illustrate the regulation of: 1. Water balance in the blood by ADH. 2. Salt balance in the blood by aldosterone.

  22. Hormones You Need to Know • Growth Hormone • Leptin • TRH TSH • ACTH • Melatonin • Serotonin • Glucocorticoids (ex: cortisol • Mineralocarticoids • ADH and Aldesterone • Adrenaline and noradrenaline • Thyroid Hormone • PTH • Glucagon • Calcitonin Know: Name Where Produced Target Organ Effects Regulation

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