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Chronic Care Plan. Programme. Long-term complications. 1. 2. Co-morbid conditions. Long-term complications. Slide no 4. Complications. Eyes (retinopathy) blindness Also cataracts Kidneys (nephropathy) kidney failure Nerves (neuropathy) decreased pain perception Blood vessels
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Programme Long-term complications 1 2 Co-morbid conditions
Slide no 4 Complications • Eyes (retinopathy) blindness • Also cataracts • Kidneys (nephropathy) kidney failure • Nerves (neuropathy) decreased pain perception • Blood vessels • Limbs peripheral vascular disease • Heart heart attacks • Brain strokes Amputations
Slide no 5 Long-term complications • Take years to develop • May occur in childhood • Glucose control (HbA1c) related to risk of complications • Early control in childhood important (metabolic memory) • Complications due to injury to blood vessels • Cause of mortality
Screening programmes Limited joint mobility (LJM)
Slide no 7 Neuropathy • Peripheral neuropathy • Painful neuritis • ‘Glove and sticking’ distribution • Loss of sensation • Reduced reflexes • Autonomic neuropathy • Alteration in gastric function (gastroparesis) • Bloating, decreased appetite, constipation, diarrhoea • Palpitations • Urinary retention
Slide no 8 Neuropathy screening • Symptoms • Neurological examination
Slide no 9 Nephropathy • Increase protein excretion • Small increase early microalbuminuria • Treatment can slow progression • Large amount of protein excretion macroalbuminuria or proteinuria • Can cause increased blood pressure • Kidney failure • Treatment is dialysis or transplant
Slide no 10 Nephropathy screening • Annual microalbumin tests • Start 5 years after diagnosis or at start of puberty • Monitor blood pressure • Treat microalbuminuria proteinuria and/or high blood pressure with medication • Improve control (i.e. decrease HbA1c)
Slide no 11 Retinopathy • Bleeding and new blood vessels in the eye • 5-10% chance of blindness • Rapid improvement of poor control can cause retinopathy to get worse • Screen from 5 years after diagnosis or at start of puberty • Eye examination • Retinoscopy • Fundus photography is better if available
Cataract / Retinal hemorrhage Slide no 12 Cataract Retinal hemorrhage
Retinal Microvascular Complications Proliferative retinopathy Normal retina
Slide no 18 Co-morbid conditions (1) • Not caused by diabetes • More common in children & adolescents with diabetes • Common genetic predisposition • Auto-immune disease • Often no clinical symptoms • Need laboratory screening
Slide no 19 Co-morbid conditions (2) • Thyroid dysfunction • Goitre, hypothyroidism, hyperthyroidism • Thyroid function tests, thyroid antibodies • Coeliac disease • Sensitivity to gluten bowel dysfunction • Often asymptomatic positive transglutaminase or endomysial or gliadin antibodies • Addisons disease • Unexplained decrease in insulin doses, hypoglycaemia, slow growth, fatigue, increased skin pigmentation • Refer for management
Slide no 20 Other issues • Osteopenia • Necrobiosis lipoidica diabeticorum • Itchy/painful hardened skin patches • Lipohypertrophy (if injection sites are not rotated correctly) • Lipoatrophy
Skin complications of insulin injections Lipohypertrophy Lipoatrophy
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