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This study investigates the use of multiple microwave probes for the treatment of hepatic tumors, aiming to increase lesion size, customization, and treatment efficiency. Results show larger lesions are achieved with multiple probes, offering improved treatment options for complex tumors and those near blood vessels.
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Microwave Ablation of Hepatic Tumors: Simultaneous Use of Multiple Probes Results in Large Areas of Tissue Necrosis Andrew Wright MD, Chris Johnson, Fred Lee Jr. MD, and David Mahvi MD Departments of Radiology and Surgery University of Wisconsin Hospital
Multiple Probe Ablation • Microwave Ablation • Goals • Increase lesion size • Increase control and customization of lesion size and shape • Decrease treatment time • Allow for treatment of multiple tumors
Hypothesis • Multiple probe hepatic ablation will result in synergistically larger lesion sizes by shielding lesion center from blood-flow mediated cooling
Methods • Microwave Ablation System • Vivant Medical • 13g, 15cm dipole antenna • 60W, 915MHz generator • 8 channels • Fiberoptic temperature monitor
Methods • Microwave Protocol • Domestic Swine • 10 minute ablation, 40 Watts • Single Probe Ablation • Multiple Probe Ablation • 3 parallel probes in triangular array • Separation between probes varied from 0.5 to 3.5cm
Methods • Microwave Protocol Single Probe Multiple Probe
Assessment • Lesion dimensions calculated • Multiple Probe lesions scored for shape
Results • Size by Separation
Results • Lesion Shape
Results • Lesion Shape
Results • Temperature
Results • 5 Probes
Conclusions • Microwave ablation may be performed with multiple, simultaneous probes • Microwave ablation with three probes results in lesions four times larger than single probe microwave ablation • Confluent lesions may be produced with probe separations of 1.6cm or less
Summary • Microwave ablation has several theoretical advantages over RF ablation • Multiple probe microwave ablation may allow for treatment of larger, more complex tumors as well as simultaneous treatment of multiple tumors • Multiple probe ablation may improve treatment of tumors near blood vessels