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Fundamental Imaging Characteristics and Resolution of Metal Alloys

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Fundamental Imaging Characteristics and Resolution of Metal Alloys

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  1. This presentation will probably involve audience discussion, which will create action items. Use PowerPoint to keep track of these action items during your presentation • In Slide Show, click on the right mouse button • Select “Meeting Minder” • Select the “Action Items” tab • Type in action items as they come up • Click OK to dismiss this box • This will automatically create an Action Item slide at the end of your presentation with your points entered. Fundamental Imaging Characteristics and Resolution of Metal Alloys By Marc G. Apple, M.D. Mark Michael

  2. Fort Wayne Metals was founded and continues to grow because of our dedication to the medical device field “Our mission is to continuously improve the quality of our products, the speed and efficiency with which we respond to our customers requests, and the knowledge of the materials we work with and recommend.” FWM’s Mission Statement

  3. Typical Wire Application Need • Diameter • Strength • Fatigue • Corrosion Resistance • Electrical Resistance • Formability But Now…

  4. Imaging • What size wire should I use? • Which alloy will work best? • Will flat wire be better than round? • How can we find answers? • What modality will you use? • What is a good image? • What technology will be used?

  5. Where did we start • Most implantable wires lose imaging capability under .004”(.1mm) • The best still perform around .001”(.025mm)

  6. The Concept • Choose wire diameters from .001” to .011” (.025mm to .28mm) • Choose common alloys and candidate alloys • Mount in stable fashion • Characterize using common modalities

  7. Wire Diameters 90 Pt 10 Ni

  8. MP35N Commercially Pure Titanium Tantalum Nitinol Platinum-10 Ni DBS(7) MP-DFT® 28Ag Coni-DFT® 33Pt Candidate Alloys and Materials

  9. Candidate Alloys and Materials • 304V • 316LVM • Gold • Platinum • L605 • Custom 455

  10. Selecting Modalities • Dr. Marc Apple at Parkview Oncology Center • Discuss imaging from a clinician point of view • Choose common modalities: Ximatron Hi-Res FluoroscopyPicker PQS CT Scanning SimulatorSiemans Magnetic Resonance Imaging

  11. Ximatron Hi-Res Fluoroscopy 100 cm source to surface distance 110kv; 25ma; 3mas, 1.5mag latitude for technician

  12. Typical Fluoroscopic Image

  13. Ximatron Image Comparison

  14. Clinician Comments • Amazed at variation due to equipment set up • Observed “zebra stripe effect” in bird’s eye view

  15. Picker “PQS” System “CT Scan” 130kv; 150ma; pitch=1.5 latitude for technician

  16. CT scan Image Reconstruction Options

  17. CT Scan of Wire Frame Thanks to Katie Shively, R.T.T. Parkview Hospital Regional Cancer Center Fort Wayne, Indiana

  18. Picker Image Comparison

  19. Variables in Imaging • Media- Impact of bolus was significant • Default equipment settings

  20. Siemens “Magnetom Harmony” magnetic resonance imaging

  21. MRI Measurement Parameters • “Magnetom Harmony” Class • 1.0 Tesla magnetic field • Operated at a 42 M#2 frequency • Used head coil with IR=415.0 • 15 internal slices with 3-D reconst • 3.00mm slice thickness, 0 skip • 192 x 256 matrix • Contrast setting W=792-798, C=369-376 • All images obtained using T-1 weighting

  22. Typical MRI Image

  23. MRI Comparison

  24. Variables in Imaging • Head coil was necessary to obtain images • Resolution was better than presented images

  25. Next Step Options • Explore impact of form on imaging (flat wire, strand, cable, shapes) • Explore surface condition impact (plating, oxides, textures) • Move on to other Modalities (Ultrasound)

  26. Conclusions • Novel pilot study to preemptively evaluate tissue equivalent characteristics before prototype devices • This protocol may prove useful as reference data for diameter and material selection

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