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Monday, April 2, 2012

Monday, April 2, 2012. Homework: - Translation Checkup tomorrow - Translation Practice due tomorrow Word Wall due on Block Day Quiz on DNA Protein - Block Day. Turn to entry from Friday:. Translation (mRNA Protein) - turn to back of the worksheet (SIDE TWO)

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Monday, April 2, 2012

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  1. Monday, April 2, 2012 Homework: - Translation Checkup tomorrow - Translation Practice due tomorrow • Word Wall due on Block Day • Quiz on DNAProtein- Block Day

  2. Turn to entry from Friday: Translation (mRNAProtein)- turn to back of the worksheet (SIDE TWO) Watch the animation and fill in the steps on the worksheet.

  3. Make a new entry: Entry 31: Translation Notes- 4/2/12 See attached

  4. D A E C B

  5. 4 Components used in Translation • mRNA- the message to be translated into protein. • Amino acids- the building blocks that are linked together to form the protein. • Ribosomes- the “machines” that carry out translation.

  6. tRNA(transfer RNA)- brings an amino acid to the mRNA and ribosome. -One end of a tRNA molecule has a 3 letter code that matches with an mRNA codon. • The other end has a specific amino acid. • A tRNA molecule with a particular 3 letter always carries the same type of amino acid.

  7. How does translation occur?

  8. How does translation occur? • The ribosome attaches to the mRNA molecule. • The tRNA attaches to the mRNA. The tRNA anticodon attaches to the mRNA codon. • The first two amino acids are joined/connected and the first tRNA leaves, and the ribosome moves along the mRNA to the next codon

  9. The next tRNA brings in the next amino acid, adding to the growing amino acid chain. • The process continues with the ribosome moving along the mRNA and the amino acids linking together until a STOP codon is reached. • The chain of amino acids folds into a working protein—based on the attraction of the side chains.

  10. The CODE of translation

  11. CODONS mRNA nucleotides are translated in groups of 3 called codons. AUGCACUGCAGUCGAUGA

  12. Each codon codes for a specific amino acid. 20 different amino acids can be used in different combinations to form a protein. For example: mRNA codonamino acid AAU CGC GGG asparagine arginine glycine

  13. - Amino Acid order determines shape. - Interactions between amino acids side chains foldsofthe chain.

  14. How is the amino acid sequence determined? • The mRNA • Each codon is a code for one amino acid DNA sequence: T A C C G A G A T T C A mRNA sequence: A U GG C UC U AA G U amino acid sequence: Met -- Ala -- Leu -- Ser

  15. Make an entry: Entry 32: Translation Practice-4/2/12 Pro Met G G A U A C

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