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Chapter 18 Integumentary System Diseases and Disorders. Anatomy and Physiology. Skin is largest organ of body First line of protection for body against invading organisms Provides sense of touch, heat, cold, and pain. Anatomy and Physiology.
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Anatomy and Physiology • Skin is largest organ of body • First line of protection for body against invading organisms • Provides sense of touch, heat, cold, and pain
Anatomy and Physiology • Helps stabilize temperature and fluid and electrolyte balance • Three layers • Epidermis • Dermis • Subcutaneous
Common Signs and Symptoms • Skin lesions • Pain • Pruritus • Edema • Erythema • Inflammation
Diagnostic Tests • Biopsy • Culture and sensitivity • Blood tests • Microscopic smear examinations
Herpes • Large family of viruses • Symptoms: inflammation of the skin, clusters or fluid-filled vesicles • Not treatable and remains in affected individual’s body for life • Remissions and exacerbations
Herpes • Common types • Herpes Simplex I - “fever blisters and “cold sores” • Herpes Genitalis, Herpes Simplex II - “genital herpes” • Herpes Varicella - “chickenpox” • Herpes Zoster - shingles
Verruca (Warts) • Chronic condition • Occur in multiples and differ in size, shape, and appearance • Often resistant to treatment
Verruca (Warts) • Common types • Appear on hands and fingers of children • Plantar warts appear on sole of the foot • Genital warts are sexually transmitted
Impetigo • Streptococcus and staphylococcus • Affects face and hands of children • Symptoms: vesicles, pustules that rupture producing yellow crust over lesions • Treatment: cleansing and antibiotic ointment
Folliculitis • Inflammation and infection of the hair follicle usually by staphylococcus • Symptoms: small pustules surrounding hair • Treatment: antibiotics
Abscess, Furuncle, Carbuncle • Inflammation, infection, and formation of a capsule prevent spread of infection • Treatment: antibiotics
Cellulitis and Erysipelas • Diffuse or spreading inflammation of skin and subcutaneous tissue • Cellulitis is caused by staphylococcus • Erysipelas is a form of cellulitis caused by streptococcus, which affects the face
Cellulitis and Erysipelas • Symptoms • Fever and chills • Headache • Vomiting • Red, painful edematous skin • Treatment: IV antibiotics
Lyme Disease • Multisystem infections transmitted to humans through bite of infected deer tick • Symptoms • Flu-like symptoms • Arthritis • Malaise
Lyme Disease • Symptoms • Chills and fever • “Bull’s eye” skin rash • Treatment—antibiotics
Tinea • Tinea • Infects warm, moist areas of body • Feeds on perspiration and dead skin • Symptoms • Itching, cracking, and weeping of skin • Treatment: Wash and dry, antifungal agents
Tinea • Forms of Tinea • Tinea Corporis: affects smooth skin on arms, legs, and body • Tinea Pedis: “athlete’s foot” • Tinea Cruris: “jock itch”
Tinea • Forms • Tinea Unguium: finger or toe nails • Tinea Capitis: scalp • Tinea Barbae: bearded areas
Candidiasis • Fungal infection caused by candida • Symptoms • Red, itchy skin with blisters and pustules • Treatment • Antifungal medications
Pediculosis • Infestation with lice • Treatment: bathing and shampooing with medicated shampoo (Kwell) • Three types of lice • Head, Body, Pubic
Scabies • Caused by tiny mite • Commonly called “seven year itch” • Slightly elevated, grayish-white lines, intense itching, vesicles, and pustules • Treatment: lindane cream to entire body
Acne Vulgaris • Inflammation of sebaceous glands and hair follicles • Symptoms: comedones • Treatment: cleansing and OTC treatments • Severe cases: antibiotics, steroids, and retinotic acid preparations
Seborrheic Dermatitis • Affects the sebaceous glands • Called “cradle cap in infants” • Affecting the scalp is “dandruff” • Symptoms: reddened, itchy areas, scales • Treatment: wash and dry, steroid creams
Sebaceous Cyst • Sebaceous gland becomes blocked and sebum collects under skin • Special type: pilonidal cyst • Treatment: incising and draining, surgical removal
Eczema • Inflammation of skin • Symptoms: itching, redness, vesicles, pustules, scales, and crusting • Treatment: topical cortisone, antihistamines, and sedatives
Contact Dermatitis • Acute or chronic allergic reaction of skin • Causes: cosmetics, laundry products, jewelry, pain • Symptoms: small red localized lesions to vesicular lesions
Psoriasis • Chronic skin disease • Symptoms: red, raised lesions with distinct borders and silvery scales • Treatment: coal tar medications, ultraviolet light, and steroids
Scleroderma • Hardening, thickening, and shrinking of connective tissues, including skin • Autoimmune reaction
Seborrheic Keratosis • Benign overgrowth of epithelial cells • Treatment • Curettage • Scraping off
Keloid • Raised, firm, irregular-shaped scar tissue following trauma or surgery • Treatment: surgical removal
Hemangioma • Congenital benign tumor of small blood vessels that form a purplish birthmark • Common types • Port wine stain • Strawberry hemangioma • Cherry hemangioma
Actinic Keratosis • Premalignant condition • Wart-like lesions on sun-exposed areas • Common in fair-skinned individuals • Treatment • Topical medication such as Retin A • Curettage or cryotherapy
Squamous Cell Carcinoma • Tends to occur in sun-exposed areas • Symptoms: firm red nodule with crusts or slightly elevated plaque • Treatment: wide surgical excision with radiation treatments
Basal Cell Carcinoma • Most common type of skin cancer • Slow-growing, locally invading tumor that does not metastasize • Treatment: surgical removal
Malignant Melanoma • Most serious type of skin cancer • Symptoms: change in size and color of mole • Rarely occurs before age 20 • May be related to severe sunburn as child
Malignant Melanoma • Treatment • Depends on degree of spread • May include wide surgical excision • Radiation and chemotherapy
Kaposi’s Sarcoma • Malignant vascular skin tumor • Bluish-red cutaneous nodules • No adequate treatment
Abnormal Pigmented Lesions • Types • Ephelis: freckle • Lentigo: liver spot • Nevus: mole • Albinism: decrease or total absence of pigment in the skin, hair, and eyes
Abnormal Pigmented Lesions • Types • Vitiligo: destruction of melanocytes in small or large patches of skin • Melasma: dark patches of skin on face, especially the cheeks
Diseases of the Nails • Abnormal shape, thickening, and color • Fungal and bacterial infections are most common cause • Bacterial infections treated with antibiotics • Fungal infections treated with antifungal medications
Diseases of the Hair • Hirsutism: excessive growth of hair • Alopecia: partial or complete hair loss
Mechanical Skin Injury • Abrasion: scraping away skin surface • Blunt trauma • Contusion by items such as a hammer or club • Thrown into items such as steering wheel and wall
Mechanical Skin Injury • Avulsion: skin or appendage is pulled or torn • Crush trauma: tissue is caught between two hard surfaces
Mechanical Injuries • Puncture injury: sharp object is forced into tissue • Laceration: cut in skin caused by a sharp object
Hyperthermia • Hyperthermia: body is overheated due to excessive exposure to sun or heat • Types • Heat exhaustion • Heat stroke
Burns • First degree: pain, redness, and swelling • Second degree: pain, redness, swelling, blisters, and open wounds • Third degree: charred and broken skin tissue, painless
Cold Injuries • Not as severe or life threatening as heat or burn injuries • Low body temperature • Symptoms: • Extreme shivering and mental confusion • Blue or cyanotic extremities and weak pulse
Cold Injuries • Treatment • Remove wet clothing • Warm body with warm blankets • Warm liquids • Frostbite: freezing of tissue, usually on face, fingers, toes, and ears
Electrical Injury • Unprotected or inadequately insulated electrical wiring • Contact with lightning • Damage has a point of entry and exit