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A. B. 12 10 8 6 4 2 0. 12 10 8 6 4 2 0. SW-480. HT-29. Fold increase (relative to control). Fold increase (relative to control). Control IR DCQ5 μ M IR+DCQ5 μ M DCQ10 μ M IR+DCQ10 μ M. preG 1 G 2 /M. preG 1 G 2 /M. preG 1
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A B 12 10 8 6 4 2 0 12 10 8 6 4 2 0 SW-480 HT-29 Fold increase (relative to control) Fold increase (relative to control) Control IR DCQ5μM IR+DCQ5μM DCQ10μM IR+DCQ10μM preG1 G2/M preG1 G2/M preG1 G2/M Treatment Treatment D 12 10 8 6 4 2 0 12 10 8 6 4 2 0 DLD-1 preG1 G2/M HCT116 Fold increase (relative to control) Fold increase (relative to control) Control IR DCQ5μM IR+DCQ5μM DCQ10μM IR+DCQ10μM Treatment Treatment Control IR DCQ5μM IR+DCQ5μM DCQ10μM IR+DCQ10μM C Control IR DCQ5μM IR+DCQ5μM DCQ10μM IR+DCQ10μM