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Parkinson’s disease. Bill Hall, Natasha Lawson, Robert Hird. James Parkinson. Apothecary Political activist Geologist Watched people from his window Talked to them in the street Wrote a treatise. Each GP will have. 3-4 patients with Parkinson’s Disease Nearly all male
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Parkinson’s disease Bill Hall, Natasha Lawson, Robert Hird
James Parkinson • Apothecary • Political activist • Geologist • Watched people from his window • Talked to them in the street • Wrote a treatise
Each GP will have • 3-4 patients with Parkinson’s Disease • Nearly all male • Mean age at onset 65 • But 5% under 40 • Genetic traits
Famous people with early PD? Ray Kennedy Michael J Fox Muahhed Ali
The classic features • Parkinson's disease is a clinical diagnosis. • Slowing of movement (bradykinesia) • Paucity of movement (hypokinesia) • Resting tremor • Rigidity • Postural instability • Asymmetric start...
Parkinson's disease unlikely if... • Frequent early falls • Prominent early dementia • Failure to respond to L-dopa therapy • Abnormal neurology • Rapid progression with early loss of mobility.
Early features • Fatigue • Stiffness • Reduced arm swing • Heavy legs • Facial expression • Resting tremor
Later features • Posture • Where is the centre of gravity?
Impact • Daily living activities • Mobility • Communication • Relationships • Sexual function • dependency
Non motor effects "doctors see Parkinson's disease as a problem from the neck up, but patients see it as a problem from the neck down."
Non motor effects • Depression • Constipation • Sleep disorders • Dementia • Incontinence • Sexual dysfunction • Sweating • Hypotension
Drugs • Levodopa • Dopamine agonists • Amantidine • Selegeline • Rasagiline • Entacapone • Anticholinergics
Drug side effects • GI effects • Extinction • Impulse control • Pathological gambling • Hypersexuality • Compulsive eating • Punding • Visual hallucinations
Teamwork • Specialist • Parkinson’s Specialist Nurse • OT • Physio • Dietician • Speech therapist • Social care • Carers
Resources • Parkinson’s Society • Information • Resources • Non-motor questionnaire • BMJ eLearning