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Applying what we know about genetics to predicting the appearance of our future offspring. The Kid Project:. Determining Your Own Phenotypes and Genotypes (as much as possible). On your sheet are a number of physical characteristics. Determine your phenotype for each trait.
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Applying what we know about genetics to predicting the appearance of our future offspring The Kid Project:
Determining Your Own Phenotypes and Genotypes (as much as possible) • On your sheet are a number of physical characteristics. • Determine your phenotype for each trait. • Determine your genotype when possible. • Determine your partial genotype (Example: E ? or A _) if you cannot determine it completely.
Gender • Under “My Phenotype” circle whether you are Male or Female. • If you are male, write “XY” under the “My Genotype” column. • If you are female, write “XX” under the “My Genotype” column.
Trait #1: Face Shape • Use “A” to represent the dominant round-shaped face and “a” to represent the recessive square-shaped face. • Decide whether the bottom half of your face is mostly square- shaped or round when viewed from the front. • Under “My Phenotype” circle which phenotype (Round or square) best matches what your face looks like. • If you have the recessive square face shape, write “aa” under the “My Genotype” column. • If you have the dominant round face shape and one of your parents has a square face, write “Aa” under the “My Genotype” column. If neither of your parents are square-faced or you don’t know if one parent is round faced, write “AA” or “A ?”under the “My Genotype” column. AA or Aa aa
Trait #2: Chin Size • Use “B” to represent the dominant “Very Prominent” chin size and “b” to represent the recessive “not prominent” chin. • Decide whether your chin is very prominent (relatively large and sticks out) or not very prominent. • Under “My Phenotype” circle which phenotype (Very Prominent or not prominent) best matches what your chin looks like. • If you have the recessive chin size, write “bb” under the “My Genotype” column. • If you have the dominant chin size and one of your parents has a chin that is not prominent (is relatively small and does not stick out a lot), write “Bb” under the “My Genotype” column. If neither of your parents have a small chin or you don’t know one parent’s chin size, write “BB” or “B ?”under the “My Genotype” column.
Trait #3: Chin Shape • Use “C” to represent the dominant “Round” chin shape and “c” to represent the recessive “square” chin shape. • Decide whether your chin is round-shaped or square-shaped when viewed from the front. • Under “My Phenotype” circle which phenotype (Round or square) best matches what your chin looks like. • If you have the recessive chin shape, write “cc” under the “My Genotype” column. • If you have the dominant chin shape and one of your parents has a chin that is square, write “Cc” under the “My Genotype” column. If neither of your parents have a square chin or you don’t know one parent’s chin shape, write “CC” or “C?”under the “My Genotype” column. CC or Cc c c
Trait #4: Cleft Chin • Use “D” to represent the dominant “Cleft chin” trait and “d” to represent the recessive trait where the cleft or dent in the chin is absent. • Decide whether or not your chin has a cleft in it. • Under “My Phenotype” circle which phenotype (Present or absent) best matches what your chin looks like. • If you have the recessive trait, write “dd” under the “My Genotype” column. • If you have the dominant cleft chin phenotype and one of your parents lacks a cleft chin, write “Dd” under the “My Genotype” column. If neither of your parents have the recessive trait or you don’t know if they do, write “DD” or “D ?”under the “My Genotype” column. DD or Dd dd
Trait #5: Skin Color • Skin color is a polygenic trait that is controlled by 3 separate genes. Use the letters E, F, and G to represent the dominant alleles for the production of the brown pigment melanin. • Look at the color chart on the right, or on page 241 of the red textbook, and decide which color most closely matches the darkest area on your face. Count the number of dominant alleles for the color you matched to and pick the phenotype from the table under the color chart to write on your sheet. • While there are actually several possible genotypes for the color you matched, use the genotype next to the color chart to decide what to write in the “My Genotype” box. ee ff gg Ee ff gg Ee Ff gg Ee Ff Gg EE Ff Gg EE FF Gg EE FF GG Phenotype No dominant alleles white One dominant allele light tan Two dominant alleles light brown Three dominant alleles medium brown Four dominant alleles dark brown Five dominant alleles very dark brown ALL dominant alleles black
Trait #6: Hair Color • Hair color, like skin color, is a polygenic trait except that is controlled by 4 separate genes. Use the letters H, I, J, and K to represent the dominant alleles for hair color. • Look at the chart on the right and find the phenotype that best matches your NATURAL hair color and write that color description . Count the number of dominant alleles for the color you matched to and pick the phenotype from the table under the color chart to write on your sheet. • While there are actually several possible genotypes for the color you matched, use the genotype next to the color chart to decide what to write in the “My Genotype” box. Phenotype Genotype . Black HH II JJ KK Very dark brown Hh II JJ KK Dark Brown Hh Ii JJ KK Brown Hh Ii JjKK Light brown Hh Ii JjKk Brown mixed with blondehh Ii JjKk Blonde hh ii JjKk Very light blonde hh ii jjKk silvery white hh ii jjkk
Trait #7: Red Colored Tints in the Hair • The naturalpresence of red tinted hairs among one’s other hairs is a trait that follows incomplete dominance rules. • This trait may be difficult or impossible to see in the darkest hair colors. • Determine if you have dark red tints, light red tints, or no red tints at all in your hair and circle the phenotype on your genetic worksheet that best matches what your natural phenotype is. • Write the genotype from the table on the right that matches up with your selected phenotype under the “My Genotype” column. Phenotype Genotype . Dark red tints L1 L1 Light red tints L1 L2 No red tints present L2 L2
Trait #8: Hair Type • As with all hair phenotypes, you should use what your NATURAL phenotype would be before coloring, curling, straightening, or applying “hair relaxer” chemicals. • Under “My Phenotype” circle the phenotype that best matches what your natural hair looks like. • Like the red tints trait, the type of hair follows incomplete dominance rules. Use the table below to determine what to write as your genotype: Phenotype Genotype . Curly or “Nappy” M1 M1 Wavy M1 M2 Straight M2 M2
Trait #9: “Widow’s Peak” • As with all hair phenotypes, you should use what your NATURAL phenotype would be (before shaving or cutting your hair along the hair line). • The presence of a widow’s peak (seen to the right) is a dominant simple Mendelian trait. Use “O” to represent the dominant allele for this gene and “o” if you lack the trait. • Under “My Phenotype” circle the phenotype that best matches what your natural hairline looks like. • If you have the dominant Widow’s Peak trait and one of your parents has a straight hairline, write “Oo” under the “My Genotype” column. If neither of your parents have the recessive trait or you don’t know if they do, write “OO” or “O?”under the “My Genotype” column. OO or Oo oo
Trait #10: Eye Color Phenotype Genotype . Black PP QQ Dark brown PPQq Brown with green tints (Hazel) Pp QQ Brown PpQq Violet PPqq Grey Blue Ppqq Green pp QQ Dark blue pp Qq Light blue pp qq • The color of the iris of your eye is a polygenic trait controlled by two separate genes. Use the letters P and Q to represent the dominant alleles for hair color. • Look at the chart on the right and find the phenotype that best matches your eye color. Write that color description in the space under “My Phenotype”. • Use the genotype next to your color in the chart to decide what to write in the “My Genotype” box.
Traits #19-21: Mouth Phenotypes (Even if you dimple on only one side when you smile, consider yourself as having the Dominant Trait.)
Trait #25: Earlobe Attachment (H H or H h) (h h)
Trait #26: “Darwin’s Earpoint” • This Dominant trait s a slight protrusion in the ridge of the ear. Present (I I or I i) Absent (ii)
Trait #27: Ear Pits • Any sort of indentation in the earlobe is an ear pit. • Pierced ears may make it hard to tell if you have this trait. • Having ear pits is the dominant trait (JJ or Jj). Present (JJ or Jj) absent (j j)
Trait #28: Hairy Ears • This dominant Mendelian trait is more noticeable when you get older. • Having hairy ears is the dominant allele for this trait Absent (k k) Present(KK or Kk)
Trait #29:Cheek Freckles • Freckles on your cheeks is a dominant trait. Present ( L L or L l ) absent (l l)
Trait #30: Forehead Freckles • Freckles on your forehead is a dominant trait. Present ( M M or M m ) absent (mm)
Trait #31: Allergies • Having allergies is a dominant trait. For simplicity we will not worry about exactly what you may or may not be allergic to. • Under “My Phenotype” circle “Present” if you have allergies of any kind. If you do not have even minor allergies, circle “absent”. • If you don’t have allergies, write “aa” under the “My Genotype” column. • If you have allergies and one of your parents does not, write “Aa” under the “My Genotype” column. If you don’t know if one of your parents is free of allergies, write “AA” or “A ?”under the “My Genotype” column.
Trait #32: Handedness • Being right handed is a dominant trait. If you are naturally ambidextrous (can use both hands equally well) consider yourself to be heterozygous. • Under “My Phenotype” circle “Right handed” if you use your right hand for most tasks. If you write with or predominantly use your left hand, circle “Left handed”. • If you are a lefty, write “r r” under the “My Genotype” column. • If you are a righty and one of your parents is left handed, write “Rr” under the “My Genotype” column. If you don’t know if one of your parents is definitely left handed, write “RR” or “R ?”under the “My Genotype” column.
Trait #33: ABO Blood Type • Knowing or finding out your blood type and that of your parents can be difficult for some people, so it this trait is only for extra credit. • Under “My Phenotype” circle your blood type if you know what it is. • If you have Type A Blood, and one of your parents has type O, write “IA i" under the “My Genotype” column. If you don’t know your parents blood type, write “IA IA" under the “My Genotype” column. • If you have Type B Blood, and one of your parents has type O, write “IB i" for your genotype. If you don’t know your parents blood type, write “IA IA" under the “My Genotype” column. • Type O blood has an “ii“ genotype, while Type AB blood has an “IAIB” genotype.
Trait #34: Tongue Rolling • The ability to roll your tongue is a dominant trait. Use the letter “T” to represent the allele for this ability. • Under “My Phenotype” circle “Can roll” if are able to roll your tongue. If you do not have the ability to do this, circle “cannot roll”. • If you can’t roll your tongue, write “tt” under the “My Genotype” column. • If you can roll your tongue and one of your parents cannot, write “Tt” under the “My Genotype” column. If you don’t know if one of your parents lacks this ability, write “TT” or “T ?”under the “My Genotype” column. Tongue-roller (TT or Tt)
Trait #35: Vision • Visual problems, like near-sightedness, that require glasses tend to be dominant traits. Use the letter “G” to represent the allele for visual problems. • Circle “Needs Glasses” if need corrective lenses to see properly. If you do not need corrective lenses, circle “does not need glasses”. • If you don’t need glasses, write “gg” under the “My Genotype” column. • If you need glasses or contacts, and one of your parents does not, write “Gg” under the “My Genotype” column. If you don’t know if one of your parents need glasses, write “GG” or “G ?”under the “My Genotype” column. ( GG or Gg ) ( gg )
Picking a “Mate” and Determining the Genotype of your Kid • You will be provided with the genetic information of someone of the opposite sex. • The genotypes of these individuals will be used for the other parent. • Use this sheet and your own phenotype/genotype sheet to fill out the “Student Worksheet” where you hypothetical child’s phenotypes and genotypes will be determined. • You will need a coin for determining which allele the child gets for traits you are heterozygous for.
Determining Phenotypes to See What Your “Kid” Will Look Like • Whenever you need to decide which allele your kid will get, flip a coin to determine whether or not they get the dominant or recessive allele. • After determining what your kid’s genotype is and writing it down on the chart, write the phenotype of the child in the far right column.
Determining Phenotypes to See What Your “Kid” Will Look Like • If you are female, circle one of the two “X” alleles under the “Allele from Mom” column. • If you are a male, flip a coin. If it lands “heads”, then circle the “X” in the “Allele from Dad” column. If it lands “tails”, then circle the “Y” in the “Allele from Dad” column. • Look at which letter your partner circled and then circle the same letter on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on the combination of X’s and Y’s, write whether your kid will be a boy or a girl in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for face shape on your phenotype/genotype sheet. If you are homozygous circle the letter that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on Child’s Genotype, write whether your kid will have a round or square face in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for chin size on your phenotype/genotype sheet. If you are homozygous circle the letter that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on Child’s Genotype, write whether your kid will have a prominent chin or a chin that is not prominenet in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for chin shape on your phenotype/genotype sheet. If you are homozygous circle the letter that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on the Child’s Genotype, write whether your kid will have a round chin or a square chin in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for Cleft Chin on your phenotype/genotype sheet. If you are homozygous circle the letter that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on the Child’s Genotype, write whether your kid will have a cleft chin or a chin without a cleft in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotypes for skin color on your phenotype/genotype sheet. For each gene you are homozygous for, circle the letter you have. • For those genes you are heterozygous for, flip a coin to decide which letter (capital or lower case) you will circle for that gene. • After you have decided which alleles you will donate for the 3 skin color genes, look at which letters your partner circled. Circle the same letters he or she did in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Use the skin color chart on the right to tell what the child’s skin color will be and write it in the far right box on your student worksheet. # of Capital Letters 0 1 2 3 4 5 6 “White” Light tan Light brown Medium brown Dark brown Very dark brown “Black”
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotypes for hair color on your phenotype/genotype sheet. For each gene you are homozygous for, circle the letter you have. • For those genes you are heterozygous for, flip a coin to decide which letter (capital or lower case) you will circle for that gene. • After you have decided which alleles you will donate for the 4 skin color genes, look at which letters your partner circled. Circle the same letters he or she did in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Use the hair color chart on the right to tell what the child’s skin color will be and write it in the far right box on your student worksheet. # of Capital Hair Color Letters Black 8 Very dark brown 7 Dark Brown 6 Brown 5 Light brown 4 Brown mixed with blonde3 Blonde 2 Very light blonde 1 silvery white none
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for Red Tints on your phenotype/genotype sheet. If you are homozygous circle the letter and number (L1orL2) that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle L1 in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle L2. • Look at which letter/number your partner circled and then circle the same letter in their column on your paper. • Write the circled letter/numbers in the box under the “Child’s Genotype”. • Based on the combination, write whether your kid has dark red tints, light red tints, or no red tints in their hair in the “”Child’s Phenotype” box.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for Hair Type on your phenotype/genotype sheet. If you are homozygous circle the letter and number (M1orM2) that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle M1 in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle M2. • Look at which letter/number your partner circled and then circle the same letter in their column on your paper. • Write the circled letter/numbers in the box under the “Child’s Genotype”. • Based on the child’s Genotype, write whether your kid has curly, wavy, or straight hair in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for Widow’s Peak hair line on your work sheet. If you are homozygous circle the letter that is the allele that you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on the combination, write whether or not your kid has a widow’s peak in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotypes for eye color on your phenotype/genotype sheet. For each gene you are homozygous for, circle the letter you have. • For those genes you are heterozygous for, flip a coin to decide which letter (capital or lower case) you will circle for that gene. • After you have decided which alleles you will donate for the 2 eye color genes, look at which letters your partner circled. Circle the same letters he or she did in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Use the chart on the right to tell what the child’s eye color will be and write it in the far right box on your student worksheet. Phenotype Genotype Black PP QQ Dark brown PPQq Brown with green tints (Hazel) Pp QQ Brown PpQq Violet PPqq Grey Blue Ppqq Green pp QQ Dark blue pp Qq Light blue pp qq
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for the distance between the eyes on your phenotype/genotype sheet. If you are homozygous circle the letter and number (R1orR2) that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle R1 in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle R2. • Look at which letter/number your partner circled and then circle the same letter in their column on your paper. • Write the circled letter/numbers in the box under the “Child’s Genotype”. • Based on the child’s Genotype, write whether your kid has eyes that are close together, average distance apart, or far apart in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for the relative size of the eyes on your phenotype/genotype sheet. If you are homozygous circle the letter and number (S1orS2) that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle S1 in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle S2. • Look at which letter/number your partner circled and then circle the same letter in their column on your paper. • Write the circled letter/numbers in the box under the “Child’s Genotype”. • Based on the Child’s Genotype, write whether your kid has large eyes, medium-sized eyes, or small eyes in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for eye shape on your phenotype/genotype sheet. If you are homozygous circle the letter that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on the combination, write whether your kid has almond-shaped eyes or round eyes in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for Eye Slantedness on your phenotype/genotype sheet. If you are homozygous circle the letter that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on the combination, write kid has horizontal eyes (UU or Uu) or eyes with an upward slant (u u) in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for the length of the eyelashes on your Parent work sheet. If you are homozygous circle the letter that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on the letter combination, write whether your kid has long or short eyelashes in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for eyebrow color on your phenotype/genotype sheet. If you are homozygous circle the letter and number (W1orW2) that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle W1 in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle W2. • Look at which letter/number your partner circled and then circle the same letter in their column on your paper. • Write the circled letter/numbers in the box under the “Child’s Genotype”. • Based on the Child’s Genotype, write whether your kid has eyebrows Darker than his/her hair (W1 W1), eyebrows the same color as his/her hair (W1 W2), or eyebrows lighter than their hair color (W2 W2) in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for eyebrow thickness on your phenotype/genotype sheet. If you are homozygous circle the letter that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on the combination, write whether your kid has thick or fine eyebrows in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for eyebrow length on your phenotype/genotype sheet. If you are homozygous circle the letter that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle the DOMINANT letter in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle the RECESSIVE letter. • Look at which letter your partner circled and then circle the same letter in their column on your paper. • Write the circled letters in the box under the “Child’s Genotype”. • Based on the combination, write whether your kid’s eyebrows are not connected (AA or Aa) or connected (aa) in the far right box on your student worksheet.
Determining Phenotypes to See What Your “Kid” Will Look Like • Look at your genotype for the relative size of the mouth on your phenotype/genotype sheet. If you are homozygous circle the letter and number (B1orB2) that is the allele you have. • If you are heterozygous, flip a coin. If it lands “heads”, then circle B1 in the “Allele from Dad” or “Allele from Mom” column (depending on whether you are male or female). If it lands “tails”, then circle B2. • Look at which letter/number your partner circled and then circle the same letter in their column on your paper. • Write the circled letter/numbers in the box under the “Child’s Genotype”. • Based on the Child’s Genotype, write whether your kid has a long mouth (B1B1), a medium-length mouth (B1B2), or a short length mouth (B2B2) in the far right box on your student worksheet.