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IgA and IgG Expression Patterns in Patients with β-Ac No cDNA Mutation

Explore the differential expression of IgA and IgG in β-Ac patients with no cDNA mutation using patient samples. Investigation revealed unique IgA and IgG profiles in Patient 1, 2, 3, and 4, 5, 6. Detailed analysis of IGHV mutations showcased distinct patterns among patients. IgM expression varied in Patient 1, 2, 3 compared to Patient 4, 5, 6, suggesting potential implications for disease profiling and treatment approaches.

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IgA and IgG Expression Patterns in Patients with β-Ac No cDNA Mutation

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  1. Supplemental Figure 1 Patient 2

  2. Supplemental Figure 2 Patient: 1 2 3 No cDNA No cDNA No cDNA -Ac -Ac -Ac -Ac -Ac -Ac IgG IgG IgG IgG IgG IgG IgA IgA IgA IgA IgA IgA Patient: 4 5 6 No cDNA -Ac -Ac -Ac -Ac IgG IgG IgG IgG IgA IgA IgA IgA

  3. Supplemental Figure 3 Patient 1 Patient 4 No cDNA -Ac -Ac -Ac IGHV 1 2 3 4 5 6 7 1 2 3 4 5 6 7 1 2 3 4 5 6 7 IgA Patient 1 Patient 4 No cDNA IGHV 1 1 1 2 2 2 3 3 3 4 4 4 5 5 5 6 6 6 7 7 7 IgG

  4. Supplemental Figure 4 No cDNA No cDNA Patient 1 2 3 1 2 3 -Ac IgM No cDNA Patient 4 5 6 -Ac -Ac -Ac -Ac IgM IgM IgM IgM

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