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Catalytic reactions

General Re -selectivity with „normal“ and Si -selectivity with „obesely“ 2-substituted, proline-derived pyrrolidines. Catalytic reactions. X-Ray-Crystal Structures of Bicyclic Oxazolidinones and  -Lactones. Structures of oxazolidinones. a 5-endo-trig process.

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Catalytic reactions

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  1. General Re-selectivity with „normal“ and Si-selectivity with „obesely“ 2-substituted, proline-derived pyrrolidines Catalytic reactions

  2. X-Ray-Crystal Structures of Bicyclic Oxazolidinones and -Lactones

  3. Structures of oxazolidinones a 5-endo-trig process

  4. Alternatively: an E2-Elimination from the strained conformation electrophile

  5. the cyclohexanone case A

  6. A1.3 A1.3 anti: sterically favoured syn: „antisteric“ polar, electrostatic, Coulombic interactions stabilization of zwitterion, intramolecular solvation hydrogen-bonding

  7. X-Ray Crystal Structures of Enamines Expected Structure of an “Obesely“ Substituted Pyrrolidino-Enamine

  8. Org. Lett.2003, 5, 3655.

  9. Stereoelectronically Assited Electrophilic Attack on an Enamine anti-Selective SE2‘-Allylic Substitution Eschenmoser, Dunitz et al. Helv.Chim.Acta 1978, 61, 3108; Israel J.Chem.1989, 29, 321 Fleming Chem.Soc.Rev. 1981, 10, 83 Seebach Chem.Ber.1983, 116, 2250

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