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Why do we follow-up patients who have had germ cell tumors?. To detect relapse: in the belief that earlier detection improves chance of cure To detect contralateral testis tumors To manage late toxicity For reassurance, support and counselling To collect data. First indication of relapse in TE
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1. How to follow-up patients Professor Gordon Rustin
Director of Medical Oncology
Mount Vernon Cancer Centre
Northwood
UK
2. Why do we follow-up patients who have had germ cell tumors?
3. First indication of relapse in TE08 stage I surveillance trial
4. Characteristics of relapse following therapy for germ cell tumour
5. Relapses > 2 years after completion of therapy for germ cell tumours
6. Localization of late relapsesOldenburg, Martin & Fossa J Clin Oncol 24: 5503-11, 2006
7. Adapting frequency of follow-up investigations to risk of relapse
8. ESMO Minimum Clinical Recommendations for Follow-up of NSGCT stage 1 on surveillance
9. ESMO Minimum Clinical Recommendations for Follow-up of NSGCT after chemotherapy
10. Royal Marsden Minimum Clinical Recommendations for Follow-up for stage 1 seminoma on surveillance
11. ESMO Minimum Clinical Recommendations for Follow-up for stage 1 seminoma after adjuvant therapy
12. ESMO Minimum Clinical Recommendations for Follow-up of seminoma after metastatic disease
13. Risks of excess CT scans
14. Definitions of Metabolic Syndrome
15. Investigations to be performed at 2, 5 and 10 years to detect late effects of therapy for germ cell tumors
16. Questions related to follow-up of patients with germ cell
17. LDH should not be measured routinely in follow-up of germ cell tumours
18. Malignant teratoma 32 years after treatment of germ cell tumor confined to testis.Pavic M, Meeus P, Treilleux I, Droz JP. Urology. 2006 Apr;67(4):846
19. How should we organise our follow-up to detect the rare very late relapse?