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Pigs are non-ruminants. Single stomach Eat feed low in fiber Humans are also non-ruminants. Definition of a non-ruminant. Parts of the digestive tract. 1. Mouth 2. Esophagus 3. Stomach 4. Small Intestine 5. Large Intestine. What does the digestive system do?.
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Single stomach • Eat feed low in fiber • Humans are also non-ruminants Definition of a non-ruminant
Parts of the digestive tract • 1. Mouth • 2. Esophagus • 3. Stomach • 4. Small Intestine • 5. Large Intestine
What does the digestive system do? • Breaks down feedstuffs into ….. • simple chemical parts….. • so the pig can absorb….. • and utilize them .
What does the mouth do in digestion? • Breaks down feed stuffs by chewing • Adds saliva to help in digestion
What does the esophagus do? • Muscles contract to move the food down to the stomach
Adds digestive juices to break down food What does the stomach do?
The small intestine…. • Mixes secretions • Absorbs nutrients
What does the large intestine do? • Storage and formation of feces • Absorption of water • Secretion and reabsorption of electrolytes
Non-ruminant • Abomasum- true stomach • depends on digestive enzymes • pepsin, rennin, trypsin, chymotrypsin, HCL • Needs • energy (fat and CHO), protein (a.a.), minerals (Ca:P 1.2:1 to 1.5:1), vitamins, water, antibiotics and other additives
Digestive secretions: saliva • Functions of saliva in non-ruminants: • Lubricates food to facilitate swallowing • Contains antibodies and lysozyme • Some amylase in saliva of swine and rats, but much less than in humans • Functions of saliva in ruminants: • Maintains fluid consistency of rumen • Slightly alkaline; helps neutralize acids formed by fermentation • May help prevent frothing in rumen
Gastric pits in gastric mucosa • Gastric pits are openings to ducts into which gastric glands empty their secretions
Exocrine gland • Any gland that directs its secretions through a duct into a compartment that is contiguous with the exterior of the body
Glandular regions of simple stomach Cardiac Fundic Pyloric
Glandular regions of equine, porcine and ruminant stomachs • Cardiac, fundic and pyloric gland regions are glandular • Esophageal regions (“E”) are non-glandular epithelium
Cardiac gland region (cardiac mucosa) Cardiac Fundic Pyloric
Fundic gland region Cardiac • Mucous neck cells • Parietal cells • Chief cells Fundic Pyloric
Fundic gland region • Mucous neck cells secrete mucus • Parietal cells secrete: • HCl • Intrinsic factor (not in cats); necessary for absorption of Vitamin B12
Fundic gland region • Chief cells secrete pepsinogen • HCl converts pepsinogen into pepsin • Pepsin is a proteolytic enzyme (breaks down proteins into peptides)
Pyloric gland region Cardiac • Mucous secreting cells • G cells Fundic Pyloric
Pyloric gland region • G cells are endocrine gland cells – secrete the endocrine hormone, gastrin • Endocrine cells secrete hormones into the bloodstream – travel to a distant part of the body where they produce an effect on another cell type
Substances that stimulate HCl secretion by parietal cell Gastrin may interact with either receptor • Gastrin • Acetylcholine • Histamine • Histamine secreted by ECL cells in gastric mucosa
Rennin • Enzyme secreted by abomasal mucosa of young ruminant • Acts to coagulate milk protein, which facilitates its digestion
Exocrine pancreatic secretions • Liquid rich in HCO3- • Pancreatic digestive enzymes • Both are secreted into duodenum
Pancreatic digestive enzymes • Pancreatic proteolytic enzymes (pancreatic proteases) are secreted as proenzymes (zymogens)
Activation of pancreatic proteases in small intestine • CCK stimulates duodenal mucosal cells to produce enteropeptidase Proelastase Elastase