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2003-2004 Review of Anticoagulants, Thrombolytics and Anti-platelet Drugs

2003-2004 Review of Anticoagulants, Thrombolytics and Anti-platelet Drugs. 1 April 2014 7:17 AM. Abciximab. Antiplatelet Anti-GPIIb/IIIa receptor antibody. Adalimumab. TNF inhibitor Anti-TNF antibody Used in rheumatoid arthritis. Allopurinol. Antigout Antineoplastic (supporting agent)

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2003-2004 Review of Anticoagulants, Thrombolytics and Anti-platelet Drugs

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  1. 2003-2004Review of Anticoagulants, Thrombolytics and Anti-platelet Drugs 1 April 20147:17 AM

  2. Abciximab • Antiplatelet • Anti-GPIIb/IIIa receptor antibody

  3. Adalimumab • TNF inhibitor • Anti-TNF antibodyUsed in rheumatoid arthritis

  4. Allopurinol • AntigoutAntineoplastic (supporting agent) • Folic acid analogueXanthine oxidase inhibitor

  5. Aminocaproic acid (EACA) • Procoagulant • Inhibitor of plasminogen activation(decreases fibrinolysis)

  6. Anistreplase • Thrombolytic • Streptokinase + plasminogen

  7. Aprotinin • Procoagulant • Fibrinolytic inhibitorSerine protease inhibitor (“serpin”)Streptokinase inhibitor

  8. Argatroban • Anticoagulant • Direct thrombin inhibitor

  9. Aspirin(Acetylsalicylic acid, ASA) • NSAID (acetylsalicylate)Analgesic, Anti-inflammatoryAntipyretic, Antiplatelet • Irreversible cyclooxygenase inhibitor

  10. Atorvastatin • Antihyperlipidemic • HMG-CoA reductase inhibitor

  11. Auranofin • Disease modifyinganti-rheumatic drug (DMARD) • Gold saltOral

  12. Aurothioglucose • Disease modifyinganti-rheumatic drug (DMARD) • Gold saltParenteral

  13. Balsalazide • NSAID (salicylate) • Treatment of IBD

  14. Beclomethasone • AdrenocorticosteroidGlucocorticoid • Anti-inflammatory steroidInhaled

  15. Betamethasone • AdrenocorticosteroidGlucocorticoid • Anti-inflammatory steroidNot by inhalation

  16. Bivalirudin • Anticoagulant • Direct thrombin inhibitor

  17. Bradykinin • Inflammatory mediator • Plasma, hypotension, pain

  18. Budesonide • AdrenocorticosteroidGlucocorticoid • Anti-inflammatory steroidInhaled OR treatment of IBD

  19. C3a, C5a • Inflammatory mediators • Anaphylatoxins Low molecular weight complement cleavage products

  20. Celecoxib • NSAIDAnti-inflammatory • Cyclooxygenase 2 (COX-2) inhibitor

  21. Cholestyramine • Antihyperlipidemic • Bile acid binding resin (BABR)

  22. Clofibrate • Antihyperlipidemic • Lipoprotein lipase activator

  23. Clopidogrel • Antiplatelet • ADP receptor antagonist

  24. Colchicine • Antigout onlyAnti-inflammatory • Microtubule inhibitor

  25. Colestipol • Antihyperlipidemic • Bile acid binding resin (BABR)

  26. Cortisol (Hydrocortisone) • AdrenocorticosteroidGlucocorticoid • Anti-inflammatory steroid

  27. Cromolyn sodium • Mast cell stabilizer • Inhibits release ofmast cell mediatorsUsed prophylactically in asthma

  28. Dalteparin • Anticoagulant • LMW HeparinATIII activator

  29. Dexamethasone • AdrenocorticosteroidGlucocorticoidAntineoplasticAntiemetic • Anti-inflammatory steroidNot by inhalation

  30. Diflunisal • NSAIDAnalgesic, Anti-inflammatory Antipyretic • Cyclooxygenase inhibitor

  31. Dipyridamole • Antiplatelet • Phosphodiesterase inhibitor(increases cAMP)

  32. Drotrecogin alfa(Activated Protein C) • Anticoagulant • Many actionsTreatment for septic shock

  33. Enoxaparin • Anticoagulant • LMW HeparinATIII activator

  34. Eptifibatide • Antiplatelet • GPIIb/IIIa antagonist

  35. Erythropoietin (EPO) • Cytokine • Primary regulator of RBC synthesis

  36. Etanercept • TNF inhibitor • Tumor necrosis factor receptor+ Fc portion of IgGUsed in rheumatoid arthritis

  37. Ezitimibe • Antihyperlipidemic • Cholesterol absorption inhibitor

  38. Fenofibrate • Antihyperlipidemic • Lipoprotein lipase activator

  39. Flunisolide • AdrenocorticosteroidGlucocorticoid • Anti-inflammatory steroidInhaled

  40. Fluticasone • AdrenocorticosteroidGlucocorticoid • Anti-inflammatory steroidInhaled

  41. Fluvastatin • Antihyperlipidemic • HMG-CoA Reductase Inhibitor

  42. Gemfibrozil • Antihyperlipidemic • Lipoprotein lipase activator

  43. Gold salts auranofin, aurothioglucose • Disease modifying anti-rheumatic drugs (DMARD)

  44. Granulocyte-Colony Stimulating Factor (G-CSF) • Cytokine • Granulocyte synthesis stimulator

  45. Granulocyte/Monocyte-Colony Stimulating Factor (GM-CSF) • Cytokine • WBC (granulocytes and monocyte) synthesis stimulator

  46. Heparin • Anticoagulant • ATIII activator

  47. Hirudin • Anticoagulant • Direct thrombin inhibitor(DTI)

  48. Histamine • Inflammatory mediator • Stored in mast cells and basophils

  49. Hydrocortisone • AdrenocorticosteroidGlucocorticoid • Anti-inflammatory steroid

  50. Hydroxychloroquine • Disease modifyinganti-rheumatic drug (DMARD)

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