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Toward Automating Patient-Specific Finite Element Model Development. Nicole M. Grosland, Vincent A. Magnotta, Kiran H. Shivanna, Steve Pieper, Curt Lisle. Patient Specific Models.
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Toward Automating Patient-Specific Finite Element Model Development Nicole M. Grosland, Vincent A. Magnotta, Kiran H. Shivanna, Steve Pieper, Curt Lisle
Patient Specific Models • In order to bring FE to the “bedside” for guiding surgical procedures the technique must be unencumbered from the image segmentation and mesh generation process • Overcome the limitations associated with individualized, or patient-specific models
Goal and Obstacles • Goal • Integrate meshing generation tool into Slicer3 that would allow for the rapid development of hexahedral meshes from imaging data • Obstacles • IA-FEMesh was relatively immature • Slicer3 was relatively immature
Solution • Moved development of IA-FEMesh to KWWidgets • Built an infrastructure that could be easily integrated into Slicer3 • Added support to Slicer3 for new types of objects • Unstructured grids • New visualization pipelines • Allowed development to progress in parallel
Integrating with Slicer3 • VTK rendering pipelines converted to use MRML display nodes for rendering in Slicer3 • Separate MRML display nodes were created for each datatype in the meshing workflow
Workflow • IA-FEMesh Module • Building Block(s) • Creation • Editing • Mesh Density • Mesh Generation • Quality Eval • Improvement • Material Properties • Constant • Image-Based • Element Sets • Boundary Conditions • Node Sets • Analysis • ABAQUS • Other packages • Ansys • Adina • Etc… • Slicer3 • Load Images • Segmentation • Manual • EMS • Surface Generation
Significant Achievements • Created a number of new 3D VTK Widgets • Developed a new workflow style to simplify mesh development • Developed a tutorial for the meshing workflow and held a workshop • Integrated this tool into a Finite Element course • Meshed a number of complex anatomic structures
Meshing Module Slicer3 Integration
Publications • Grosland NM, Bafna R, Magnotta VA., Automated hexahedral meshing of anatomic structures using deformable registration. Comput Methods Biomech Biomed Engin. Comput Methods Biomech Biomed Engin. 2009 Feb;12(1):35-43. [PMC Journal - In Process] • Grosland NM, Shivanna KH, Magnotta VA, Kallemeyn NA, DeVries NA, Tadepalli SC, Lisle C., IA-FEMesh: An open-source, interactive, multiblock approach to musculoskeletal finite element model development, Comput Methods Programs Biomed. 2009 Apr;94(1):96-107. [NIHMS101589] • Kallemeyn NA, Tadepalli SC, Shivanna KH, Grosland NM, An interactive multiblock approach to meshing the spine, Comput Methods Programs Biomed. 2009, Sep;95(3):227-35.. • DeVries NA, Shivanna KH, Tadepalli SC, Magnotta VA, Grosland NM, IA-FEMesh: Anatomic FE models – a check of mesh accuracy and validity. Iowa Orthop J, Iowa Orthop J. 2009; 29: 48–54. [PMCID: PMC2723692] • Tadepalli, S.C., K.H. Shivanna, V.A. Magnotta, N.A. Kallemeyn, and N.M. Grosland, Toward the development of virtual surgical tools to aid orthopaedic FE analyses. Advances in Signal Processing (Special edition: Image Processing and Analysis in Biomechanics), 2009 (accepted). • Ramme AJ, Shivanna KH, Magnotta VA, Grosland NM, Automated Building Block Definitions to Aid Multiblock Hexahedral Meshing of Bony Structures (submitted). • Shivanna KH, Magnotta VA, Grosland NM, Feature based multiblock finite element mesh generation, Comput Methods Programs Biomed. (submitted)
Status • Meshing workflow is complete • All 3D widgets work in Slicer3 • Completing sharing of data between Slicer3 and meshing module • Scheduling visit to Iowa by Curt Lisle to complete this work • Putting final touches on testing framework
Future Work • Submission of software development and maintenance grant • Mesh improvement strategies • Automate building block definitions • Mapped meshing • Renewal of NA-MIC Collaboration Grant (EB005973) • Development of tools to simulate surgical simulations • Enhancements of meshing algorithms to accommodate increasingly complex anatomical structures • Mesh improvement strategies • Validate these approaches
Acknowledgements • Grant funding NIH/NIBIB • R21 (EB001501) • R01 (EB005973) • Nicole Kallemeyn, Nicole DeVries, Esther Gassman, Ritesh Bafna, Srinivas Tadepalli, Austin Ramme, Wen Li,Dr. Brian Adams