Alcoholic Cerebellar Degeneration

907-1. Alcoholic Cerebellar Degeneration. Clinical Syndrome. The clinical syndrome of alcoholic cerebellar degeneration is remarkably stereotyped. The usual presentation, as in this patient, is a progressive unsteadiness in walking evolving over months and years. Clinical Syndrome.

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Neurology - cerebellar

Neurology - cerebellar. PULSE: Preparation for Finals Tutor name. TuBS attendance. https://tutorialbooking.com/. Session overview. Common cerebellar pathologies How to present your findings Demonstration of clinical signs Case presentations and OSCE questions.

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Cerebellar Cortical Atrophy in C57BL

Multiple Sclerosis. InflammatoryNeurodegenerative. MRI in Multiple Sclerosis. Relapses: White Matter Lesions Gadolinium EnhancingNew T2Disability: Beyond the LesionNormal Appearing White Matter (NAWM)Grey Matter. Brain Atrophy on MRI in MS. Brain Parenchymal Fraction (BPF) decreased in MSR

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Cerebellar Ataxia

Cerebellar Ataxia. Functional Role of the Cerebellum. It is only 10% of brain’s volum Contains > than half the total # of neurons in the brain. Regulates vestibular, spinal and cortical mechanism through reciprocal neuronal connections. . Functional Role of the Cerebellum cont.

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Atrophy (n)(v)

Atrophy (n)(v). (n) Wasting away of tissue; (v) to waste away ** if your muscles atrophy, you can’t win a trophy. Bastion (n). A fortified place, stronghold **base station – strong protection. Concord (n). A state of agreement, harmony; treaty, pact ** chords are played in harmony

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CEREBELLAR DYSFUNCTIONS

CEREBELLAR DYSFUNCTIONS LECTURE-30 (20 APRIL 2013) 1-2 PM Professor Dr Wahengbam PS AL Waheed MBBS,MD(PSM),MD(Medicine ).

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Temporal Atrophy

Temporal Atrophy. Hoyt IIA2_03a-b.

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Posterior Cortical Atrophy

Posterior Cortical Atrophy. Posterior Cortical Atrophy. What is PCA?. Epidemiology - how rare and where is it?. Neuropsych and clinical features – what are the symptoms?. Visuospatial and visuo- perceptual impairments Alexia. Symptoms: Bálint ’ s syndrome. Simultanagnosia dorsal

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C57BL/6OlaHsd

C57BL/6OlaHsd. Tramp and Lady. Cre-lox. C3H/HeSn- ash/+. USA PATRIOT.

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A : Tumor progression in C57BL/6 Mice

In vivo Analysis. A : Tumor progression in C57BL/6 Mice. 600. 500. 400. B16.F10. B16.F10 TFG HTLV-1 ZEO. 300. B16.F10 TFG FGF-2 ZEO. Mean tumor size (mm2). B16.F10 TFG EMCV ZEO. 200. B16.F10 DFG70 and DFG80. 100. 0. 0. 4. 8. 12. 15. 19. Days. B : Tumor progression in BALB/c.

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Atrophy

Atrophy. (n.) the wasting away of a body organ or tissue; any progressive decline or failure (v.) to waste away How to remember- in order to earn A TROPHY, one must not ATROPHY their talent and if they choose to do so, their time will have been an ATROPHY. Bastion.

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Cortical plaques

Cortical plaques. Lambotin et al , J Cell Science 2005. Ezrin. Actine (nid d’abeille). GTPases. Doulet et al , J Cell Biol 2006. PI3K. Nécessaire à l’adhésion "forte" en condition de flux (G. Mikaty, G. Dumenil & coll). Lambotin et al , J Cell Science 2005. β -arrestins. A. B.

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CEREBELLAR FUNCTION

CEREBELLAR FUNCTION. NBIO 401 Robinson. Objectives: There are 6 signs of cerebellar damage. For each sign accurately describe: what part of the cerebellum is damaged to cause that sign the characteristics of that sign

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Atrophy

Encoding. SRM. SRM. SRM. Physical Performance (short). Adapt & Learn (medium). Evolve or Persist (long). Atrophy. Design of Self-Replicating Machines. SRM. time. Consider a Cell. Signaling Pathway. Yeast. Cell Cycle. Signaling Pathway. Consider a Different Cell. Yeast.

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Cerebellar Tons – aMPFC

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Learning rules in cerebellar plasticity

Learning rules in cerebellar plasticity. Timing-based learning rules and coincidence detection: Behavioral - Cerebellar motor conditioning Molecular - IP 3 receptors Synaptic - Long-term depression at Purkinje neurons Spatial learning rules and spreading plasticity

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C57BL/6

CEA424/Tag-CEA-transgen ic mice (H-2 b ). CEA424/Tag-transgenic mice (H-2 b ). spontaneous g astric carcinoma. Established cell lines (CEA424/Tag-CEA) mGC11 CEA mGC2 CEA mGC4 CEA. Established cell lines (CEA424/Tag) 424GC mGC3 mGC5 mGC8. transplantable. transplantable. C57BL/6.

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Spinal Muscular Atrophy

Spinal Muscular Atrophy. By Robert Johnson. symptoms Infant. Can have a breathing difficulty Difficulty feeding, food may go down windpipe instead of stomach Floppy infant, poor muscle tone Lack of head control Little movements. Symptoms child. Much less symptoms then infant

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Spinal Muscular Atrophy

Spinal Muscular Atrophy. the number one genetic killer of infants and toddlers. Leena Shah Human Anatomy April 21, 2010. Samir died at 7 ½ months. Hailey Mae died at the age of 2. Owen died at 19 weeks and 6 days. Baylee died at 15 months. Spinal Muscular Atrophy (SMA).

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Cortical structures

Cortical structures eg pain, fear, sights, smells, raised ICP: Benzodiazepines & steroids. ?GABA. Vomiting centre levomepromazine Hyoscine Cyclizine*. M H1 5-HT2 . Vestibular Apparatus Levomepromazine Cyclizine* Hyoscine.

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Cerebellar system

Cerebellar system. Compiled by András Csillag. Lewis (1918) Gray's Anatomy 20th ed. Regional division of cerebellum. The classic view. Functional division and numbering according to Larsell. Deep cerebellar nuclei. Nucleus interpositus. Cerebellar cortex.

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Alcoholic Cerebellar Degeneration

907-1. Alcoholic Cerebellar Degeneration. Clinical Syndrome. The clinical syndrome of alcoholic cerebellar degeneration is remarkably stereotyped. The usual presentation, as in this patient, is a progressive unsteadiness in walking evolving over months and years. Clinical Syndrome.

133 views • 10 slides