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Professor Annie S. Anderson Centre for Public Health Nutrition Research Centre for Research into Cancer Prevention and Screening Ninewells Medical School, University of Dundee email: a.s.anderson@dundee.ac.uk. Obesity prevention and control
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Professor Annie S. Anderson Centre for Public Health Nutrition Research Centre for Research into Cancer Prevention and Screening Ninewells Medical School, University of Dundee email: a.s.anderson@dundee.ac.uk Obesity prevention and control Lessons from campaigns, intervention and advocacy Obesity – the elephant in the room in cancer communities @anniescotta @thescpn
What % cancer could be prevented in the UK if everyone was a healthy weight? http://www.wcrf-uk.org/uk/preventing-cancer/lifestyle-st19atistics/body-fatness
Evidence Base for Action Success has many parents!
Why explore the screening setting? • Screening “awakens curiosity” about disease and causes (Bankhead et al, 2003) • Existing healthcare setting and structure • Re-enforcement of public health efforts • Endorsement by cancer experts (as opposed to prevention messages from corn flakes packets, newspapers etc)
Shared and accepted understanding of lifestyle and risk? “You're lucky or you're unlucky...if it's going to be, it's going to be.” “if it's for you, it won't go by you, whether or not you do all these things”
Link between lifestyle factors and adenoma • No information received on possible contributory factors, nor on prevention of recurrence
People don’t want to know about lifestyle things at this age
BeWEL Recruitment – people are interested in lifestyle intervention Adults screened positive for adenoma aged 50 to 74 years (n=997) Responded ‘No’ n= 345 (35%) Did not respond n=160 (16%) Changed mind n=42 (9%) Responded ‘Yes’ n=492 (49%) • Ineligible • BMI <25kg/m2 n=108(22%) • ‘Yes’ ineligible as reply received after study closing to recruitment n=13(3%) Randomised n=329
Baseline and Clinical Characteristics at Randomisation Data are mean ± SD or number (%) unless stated otherwise. *Scottish Index of Multiple Deprivation
Worried unwell …Type 2 diabetes among an overweight population of adults screening positive for colorectal adenoma (Steele et al, 2015, Colorect Dis) Randomised n=329 Existing Type 2 Diabetes n=47(14.3%) Incomplete biochemistry n=32 (9.7%) Diabetes risk assessment n=250 Low to moderate risk FPG<5.5 mmol/l or HbA1c <42 mmol/l (6.0%) n=106 (42.4%) Type 2 Diabetes FPG 7.0 mmol/l or HbA1c 48 mmol/l (6.5%) n=19 (7.6%) High risk FPG 5.5 - 6.9 mmol/l or HbA1c 42 - 47 mmol/l (6.0 – 6.4%) n=125 (50.0%)
Over a 12 month period: • Retention 91% • Weight loss 3.50kg (CI 2.70 to 4.30) • Significant reduction in blood pressure, blood glucose, diet, physical activity, waist circumference • Cost £172 (£3.30 pw) plus travel and admin • Recruited – 74% men, mean age 63.6 years, 35 % in SIMD 1 and 2
Conclusions • Screening settings offer an opportunity for expert endorsement of lifestyle change for older adults, men and wide SES • Absence of advice may create health certificate effect • People ARE NOT knowledgeable about lifestyle and CRC • People ARE interested in lifestyle intervention related to CANCER • People with adenomas do respond positively to intervention initiation and maintenance • Interventions can have positive effects on body weight and other health outcomes Lets not wait till diagnosis…………………….