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Formability of 3D tissue constructs. Effect of Direct Cell Writing on cell viability. Hepatocyte Cell Viability as a Function of DCW Process and Crosslinking. Static 2D monolayer control. Dynamic 3D bioprinted experimental group. Effect of Direct Cell Writing on cell proliferation.
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Effect of Direct Cell Writing on cell viability Hepatocyte Cell Viability as a Function of DCW Process and Crosslinking Static 2D monolayer control Dynamic 3D bioprinted experimental group
Effect of Direct Cell Writing on cell proliferation Media w/o cells Std Method cell suspension using conventional pipet
Effect of Direct Cell Writing on cell-specific function DCW encapsulated cells offer: • Tight control of spatial dist. • High cell density • Co-culture multiple cell types • 3D tissue construct Resemble In Vivo Tissue: • Cell-cell communication • Direct contact • Paracrine • ECM production from neighboring cell Importance: • Function/behavior • Differentiation • Proliferation
Pic From: Computer-Aided Design, Modeling, and Freeform Fabrication of 3D Tissue Constructs for Drug Metabolism Studies