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In the name of Allah, the Beneficent, the Merciful. . TRIGEMINAL NEURALGIA. Also known as… TIC DOULOUREUX PROSOPALGIA SUICIDE DISEASE NEURALGIA EPILEPTIFORME By: Aleshba Saba Roll # 02
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TRIGEMINAL NEURALGIA Also known as… TIC DOULOUREUX PROSOPALGIA SUICIDE DISEASE NEURALGIA EPILEPTIFORME By: Aleshba Saba Roll # 02 3rd Year BDS A neuropathic disorder of trigeminal nerve
(INTRODUCTION) TRIGEMINAL NEURALGIA Sudden, usually unilateral Brief, stabbing , electric shock like recurrent pain
Pain is limited to the sensory distribution of trigeminal nerve that includes middle face(maxillary division V2)–being most frequentlyinvolved, lower (mandibular division V3) & upper(ophthalmic division V1)–being least frequently involved
Etiology • Vascular abnormality(venous or arterial) that causes compression of trigeminal root, adjacent to pons in posterior cranial fossa • Association with MS • Tumors in post. Cranial fossa (2%) • Focal nerve injury • As a result of aging, shingles, unknown causes mostly
Normal Neurovascular compression
Incidence • Usually develops after theage of 50, although there have been cases with patients being as young asthree yearsof age • 150 per 1million (estimated) people suffer from TN • Women are more likely to be affected than men (female:male – 2:1) • Usually unilateral (3% cases show bilateral involvement)
Triggering factors • Shaving, washing • Stroking your face (trigger zones on face) • Eating • Drinking • Brushing your teeth • Talking • Putting on makeup • Encountering a breeze • Smiling
Pain in areas supplied by CN V • Usually unilateral • Sharp, stabbing, electric shock like pain • Lasts for few seconds to minutes • This transient attack may be repeated in matter of minutes or hours SYMPTOMS
TYPES OF TRIGEMINAL NEURALGIA
Pre-trigeminal neuralgia • Odd sensations of pain, (such as a toothache) or discomfort (like “pins and needles”), may be symptoms of pre-trigeminal neuralgia • Occur in 20% of patients who develop TN • Pre-TN is most effectively treated with medical therapy used for typical TN
Diagnosis & Management
History • Examination(Odontogenic structures, cranial nerve functions, related structures-muscles,TMJ,sinuses) • Investigations Diagnostic local anesthetic nerve block (defines distribution of the pain, eliminate or confirm referred pain) Nerve conduction tests Imaging techniques (eliminate pain due to any other reason-odontogenic, sinus, postherpetic neuralgia, cluster headache, TMJ DS, atypical facial pain)
1st step of treatment- Pharmacotherapy(Medical management of TN) Trigeminal neuralgia is usually treated with drugs called anti- convulsants which include: • Carbamazepine (drug of choice) (400-1000mg/day) • Phenytoin (300mg/day) • Oxycarbazepine • Gabapentin (600-1200mg/day) • Baclofen, lamotrigine, clonazepam
2nd step of treatment- Surgery • Surgical options include: • Peripheral • Cryotherapy • Neurectomy • Alcohol injections • Gasserian ganglion • Radiofrequency, thermocoagulation • Glycerol injection • Microcompression (balloon compression) • Posterior fossa • Neurovascular decompression • Stereotactic radiosurgery
Non drug therapies • Trancutaneus electric nerve stimulation • Laser • Rhizotomy • Alcohol injections
There are some things that a patient can do to minimize the frequency and intensity of TN attacks: • Apply ice packs. Cold often numbs the area and will reduce the pain 2.Get adequate rest in normal rest cycles 3.Manage your stress well and keep stress levels low 4. Avoid foods that may act as nerve stimulants, such as coffee, tea, and foods that are high in sugar 5. Maintain adequate hydration and electrolyte levels 6.Practice healthy living principles such as diet and exercise
Reference www.google.com (free search) Lecture notes by Dr. Razzaq Tyldesley’s oral medicine Cawson’s Essentials of Oral Medicine P-J Lamey- A clinical guide To Oral Medicine If you suffer, thank God! it is a sure sign that you are alive. -Elbert Hubbard