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OTC Products For . Skin Disorders . Made by alaa belal. Disorders . Hyperkeratosis . Fungal Infections. Canker sores. Viral Infections. Skin Infestations . Secondary bacterial infections . Fungal Infections . Tinea. 5. Types. P edis. C orporis. C apitis. U nguium. V ersicolor.
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OTC Products For Skin Disorders Made by alaabelal
Disorders Hyperkeratosis Fungal Infections Canker sores ViralInfections SkinInfestations Secondary bacterial infections
Tinea 5 Types Pedis Corporis Capitis Unguium Versicolor
1- Tineapedis Athlete’s foot NOT just athletes !! But also: Weak immune system Older than 60 Diabetics
1- Tineapedis Athlete’s foot Interdigital Moccasin Vesicular Most common type Itching Scaling Maceration & Foul odour Between two smallest toes Burning
1- Tineapedis Athlete’s foot Interdigital Moccasin Vesicular Itching Scaling Dryness Absence of vesicles Involve the entire sole of the foot and extend onto the sides
1- Tineapedis Athlete’s foot Interdigital Moccasin Vesicular Least common Fluid-filled blisters Patient can not walk Itching Scaling
Differential diagnosis Tineapedis Eczema Inflammation, endogenous cause Differences: Redness 1) Edema 2)Oozing Blister 3)No foul odour • Similarities:Itching Crusting
3- Tineacorporis Ringworm 1)Anywhere except face, feet, hands, groin 2)Outer part of the sore can be raised, scally red, may contain vesicles, middle part normal Grows outwards, may overlap Scaling Itching
Differential diagnosis Tineacorporis Discoid eczema • Differences : • 1)Occurs on arms, hands & feet • 2)smaller • 3)Middle part is not normal 4)Rare in patients under 20 years
Differential diagnosis Tineacorporis Psoriasis Immunological problem Differences: Not contagiousRed plaques covered with silvery-white scales Painful and sometimes crack &bleed • Similarities:Itching Scaling
4- Tineacapitis Ringworm of the scalp Round, baldpatches More common in children Scaling, itching
5- Tineaunguium Onycholysis, fungal nail infection 1)Turn yellow or white 2)Get thicker
6- Tineaversicolor Pityriasisversicolor • Yeast pitysporumorbiculare • Common in oily surfacesteenagers • Not contagious Cosmetic concern
Differential diagnosis Vitiligo Tineaversicolor Found on fingers, toes, knees, and around the eyes and mouth Flat Hypo- or hyperpigmentationSlight itching and scallingNot painful Loss of all color (depigmentation) No scaling
Transmission of tinea Prevention 1. Dry off well 2. Do not wear occlusive clothes 3. Wear shower sandals at public showers and swimming pools Water
Transmission of tinea Prevention Do not share clothes, socks, towels, nail clippers Indirect contact
Transmission of tinea Prevention Avoid contact with infected people or animals Direct contact
Transmission of tinea Autoinfection
Treatment of all fungal infections Objective • Prevent recurrence • Inhibit the growth of fungus • Relieve itching, burning and other symptoms
Pharmaceutical Treatment Most fungal infections • Most fungal infections topical OTC • cream , solution ,spray , powder • But : • 1) nail 2)scalp oral prescription • Example :itraconazole (sporanox ®) and fluconazole (diflucan ®), terbinafine (lamifen®) Disadvantages of oral antifungal: • 1)most very expensive. (lamifen52 LEsporanox 42LE diflucan 1 tablet for 27LE ) • 2) side effects. contraindicated in patients with liver or heart problems. Topical OTC cream, solution, spray, powder Scalp Except • Oral prescription Nail
Oral prescription • Most fungal infections topical OTC • cream , solution ,spray , powder • But : • 1) nail 2)scalp oral prescription • Example :itraconazole (sporanox ®) and fluconazole (diflucan ®), terbinafine (lamifen®) Disadvantages of oral antifungal: • 1)most very expensive. (lamifen52 LEsporanox 42LE diflucan 1 tablet for 27LE ) • 2) side effects. contraindicated in patients with liver or heart problems. Itraconazole
Oral prescription • Most fungal infections topical OTC • cream , solution ,spray , powder • But : • 1) nail 2)scalp oral prescription • Example :itraconazole (sporanox ®) and fluconazole (diflucan ®), terbinafine (lamifen®) Disadvantages of oral antifungal: • 1)most very expensive. (lamifen52 LEsporanox 42LE diflucan 1 tablet for 27LE ) • 2) side effects. contraindicated in patients with liver or heart problems. Fluconazole
Oral prescription • Most fungal infections topical OTC • cream , solution ,spray , powder • But : • 1) nail 2)scalp oral prescription • Example :itraconazole (sporanox ®) and fluconazole (diflucan ®), terbinafine (lamifen®) Disadvantages of oral antifungal: • 1)most very expensive. (lamifen52 LEsporanox 42LE diflucan 1 tablet for 27LE ) • 2) side effects. contraindicated in patients with liver or heart problems. Disadvantages Side effects Very expensive
Treatment of nail infection(Tineaunguium) Refer to a dermatologist if • Unrespon-siveness treatment More than 2 infected nails peripheral circulatory disorders Under 18 years Deficiency in immune system Nail dystrophy or destruction Pregnancy or breast feeding diabetes mellitus
Treatment of nail infection(Tineaunguium) Oral lamifen Nail polish Ticonazole Surgically
Nail polish Cleaning Cutting Apply Twice daily, for 3 months
Treatment of scalp infection(Tineacapitis) if Refer to a dermatologist Severe alopecia Swollen mass discharging pus Swollen tender lymphocyte of the neck
Treatment of scalp infection(Tineacapitis) Oral prescription Preventing reinfection Shampoo If treated early, the hair will grow back
Treatment of tineaversicolor Skin may not regain its normal pigmentation Commonly comes back after treatment
Treatment of tineaversicolor Selenium sulfide Tinasel® Sulfiselen® Areas affected lathered by selenium sulfide for about 2-5 minsthen washed thoroughly Used dailyfor up to 2 weeks
Tineaversicolor Tineacapitis Tineaunguium
Treatment Azoles Miconazole nitrate 2% Thiocarbamates Allylamines Clioquinol Undecylenic acid Povidoneiodine
Treatment Azoles Ketoconazole 2% Thiocarbamates Allylamines Clioquinol Undecylenic acid Povidoneiodine
Treatment Azoles Available in all dosage forms Thiocarbamates Broad spectrum antifungal Allylamines Apply twice daily 2 weeks for skin infection4 weeks for foot6 weeks for scalpfew months for nail infection Clioquinol Undecylenic acid Miconazole(Daktarin®) safe in pregnancy Povidoneiodine
Treatment Azoles Tolnaftate 1% Thiocarbamates Allylamines Clioquinol Undecylenic acid Povidoneiodine
Treatment Azoles Thiocarbamates Cream and solution only Allylamines Effective against most dermatophytesnot only t.versicolor or candidiasis Clioquinol Undecylenic acid Povidoneiodine
Treatment Azoles Terbinafine 1% Thiocarbamates Allylamines Clioquinol Undecylenic acid Povidoneiodine
Treatment Azoles Thiocarbamates Cream, solution, spray tablets (but not otc) Allylamines Cream 1-2 times:1 week for T.pedis 2 weeks for T.corporisT.versicolor Clioquinol Undecylenic acid Povidoneiodine Not for children <16 or breast feeding mothers
Treatment Azoles Salt of aluminiumclioquinol 3% Thiocarbamates Allylamines Clioquinol Undecylenic acid Povidoneiodine Clioquinol + corticosteroid
Treatment Azoles Thiocarbamates Lotion, cream, ointment • Side effects of clioquinol: • May cause itching, allergic contact dermatitis • Interfere with thyroid function Allylamines Clioquinol Undecylenic acid Povidoneiodine Do not use <2 years
Treatment Azoles Thiocarbamates Undecylenic acid 10% and 25% Allylamines Fungistatic Clioquinol Undecylenicacid Ointment at nighttime Powder at daytime Povidoneiodine
Treatment Azoles Thiocarbamates Povidone iodine 10%solution (Betadaine®) Allylamines Clioquinol Undecylenic acid Povidoneiodine
Candidiasis Most common type of yeast infection More than 20 species Candida albicans(Monilia) Most common Oral thrush Causes Vaginal candidiasis
Oral candidiasis (Oral thrush) (Moniliasis) Symptoms Thick, white lacy patches on top of a red base Where ?? TonguePalateOr elsewhere inside the mouth
Treatment Topical oral antifungal 1- Miconazole 2- Nystatin
Treatment 1- Miconazole Daktarin® oral gel Miconaz® oral gel