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Blood Typing. Catalyst: In camels, having a large hump is dominant over having a small hump. Create a Punnett square to show the potential offspring of a heterozygous camel and a camel with a small hump. Make sure to list the genotype and phenotype percentages!. Write in complete sentences!
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Blood Typing • Catalyst: • In camels, having a large hump is dominant over having a small hump. • Create a Punnett square to show the potential offspring of a heterozygous camel and a camel with a small hump. • Make sure to list the genotype and phenotype percentages! Write in complete sentences! Don’t talk during the Catalyst!
Have you ever wondered… • Why we have different types of blood? • Why could you die if you get a transfusion of the wrong type of blood?
Objectives By the end of today, SWBAT… • Identify blood type genotypes and phenotypes • Determine the correct type of blood to transfuse into a patient
Agenda • Catalyst/HW Review • Quiz • Types of blood • Are you a positive person? • Whiteboards practice • VIDEO GAME PRACTICE • Exit Question
Blood Typing • Sometimes there are more than two alleles for a trait. The most important case for you to learn about is… blood type! • Key Point #1: Blood type has three alleles: IA, IB, and i. • IA and IB are both dominant (co-dominant). • i is recessive.
Types of blood • IA and IB are co-dominant • IA IA = Type A • IB IB = Type B • IA IB = Type AB • i is recessive • IA i = Type A • IB i = Type B • i i = Type O Since IA and IB are both dominant, they are expressed at the SAME TIME
Antigens and Antibodies • Key Point #2: Antigens determine blood type. Antibodies attack antigens. • If you receive the wrong type of blood, your antibodies will attack the new antigens, causing blood cells to clump and crack. Type A blood has A antigens, and B antibodies. Type B blood has B antigens, and A antibodies. Type AB blood has A and B antigens, and no antibodies Type O blood has no antigens, and A and B antibodies
Positive or Negative • Key Point #3: Rhesus factor determines if your blood type is positive or negative • If you have Rh factor, your blood is positive • If you lack the Rh factor, your blood is negative
Whiteboards • For each problem… • Determine the blood type • Determine if the person can receive the transfusion • If the person CANNOT receive the transfusion, explain what will happen if the wrong type blood is given to them
Guided Practice • Bob Dylan’s blood is IAIA, and lacks Rh factor. • What type blood does he have? • Can he receive Type B blood? • Can he receive Type O blood?
Guided Practice • D’Angelo’s blood is IBi, and has Rh factor. • What type blood does he have? • Can he receive Type AB blood? • Can he receive Type B blood?
Guided Practice • Goapele’s blood is IAIB, and lacks Rh factor. • What type blood does she have? • Can she receive Type B Rh- blood? • Can she receive Type A Rh+ blood?
Guided Practice • Dave Grohl’s blood is ii, and has Rh factor. • What type blood does he have? • Can he receive Type O Rh+ blood? • Can he receive Type AB Rh- blood?
Guided Practice • Kid Cudi’s blood is IAIA, and lacks Rh factor. • What type blood does he have? • Can he receive Type O Rh- blood? • Can he receive Type AB Rh+ blood?
Guided Practice • Nujabes’s blood is IBi, and has Rh factor. • What type blood does he have? • Can he receive Type B Rh- blood? • Can he receive Type A Rh+ blood?
Guided Practice • Drake’s blood is IAIB, and lacks Rh factor. • What type blood does he have? • Can he receive Type A Rh- blood? • Can he receive Type B Rh+ blood?
Guided Practice • Lady Gaga’s blood is ii, and has Rh factor. • What type blood does she have? • Can she receive Type AB Rh+ blood? • Can she receive Type O Rh- blood?
SICK VIDEO GAME • http://nobelprize.org/educational_games/medicine/landsteiner/landsteiner.html
Exit Question • Lil’ Wayne’s blood is IAi, and has Rh factor. • What type blood does he have? • Can he receive Type A Rh- blood? • What will happen if he donates blood to someone who is Type AB Rh-? Write in complete sentences! Don’t talk during the Exit Question!