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Example of Multiple Alleles

Example of Multiple Alleles. Human blood type is controlled by three alleles – I A , I B and i. Alleles I A and I B are dominant over i, but I A and I B are codominant. RH Factor. Inherited from our parents Independent of the ABO blood type alleles.

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Example of Multiple Alleles

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  1. Example of Multiple Alleles • Human blood type is controlled by three alleles – IA, IB and i. Alleles IA and IB are dominant over i, but IA and IB are codominant

  2. RH Factor • Inherited from our parents • Independent of the ABO blood type alleles. • 2 different alleles for the Rh factor known as Rh+ and Rh-. • Someone who is "Rh positive" or "Rh+" has at least one Rh+ allele, but could have two. Their genotype could be either Rh+/Rh+ or Rh+/Rh-. Someone who Rh- has a genotype of Rh-/Rh-. • Each biological parent donates one of their two Rh alleles to their child.

  3. http://www.biology.arizona.edu/human_bio/problem_sets/blood_types/btcalcA_popup.htmlhttp://www.biology.arizona.edu/human_bio/problem_sets/blood_types/btcalcA_popup.html

  4. Pedigree Charts: Chart that shows the relationship within a family

  5. We need your help…..

  6. The Case: As a bolt of lightning flashed above Black Mourning Castle, a scream echoed from the den of Lord Hooke. When the upstairs maid peered through the door, an arm reached for her neck. Quickly, the maid bolted from the doorway, locked herself in the library, and telephoned the police. Inspector Holmes arrived to find a frightened maid and the dead body of Lord Hooke. Apparently, the lord had been strangled. The inspector quickly gathered evidence. He noted blood on a letter opener, even though Lord Hook did not have any cuts or abrasions. The quick-thinking inspector gathered all the members of the family and began taking blood samples. The chart below shows the relatives who were in the castle at the time of Lord Hooke’s murder.

  7. The Hooke Family:

  8. The inspector gathered the following information: FAMILY MEMBER Blood Type Rh factor Lord Hooke AB + Lady Hooke A + Helen A + Roule O + Henry refused blood test Ida A - Ann B + Tom O - Jane A + Beth B - Tina A +

  9. Inspector Holmes needs your help---Detective Work: • What do we know? • What do we need to know?

  10. The blood sample on the letter opener was determined to be: Type O, Rh negative

  11. The murderer is: __________________ The motive is: ____________________

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